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International Journal of Bioprinting Micro/nano-3D hemostats for rapid wound healing
responses caused by implanted materials are significant References
obstacles to fabricated agents and devices [149,150] . We must
also consider the dynamic environment of the ECM and 1. Phillips R, Friberg M, Lantz Cronqvist M, et al., 2020,
the ways changes in fabricated micro/nanostructures Visual blood loss estimation accuracy: Directions for future
can potentially affect the physical, biochemical, and research based on a systematic literature review. Proceedings
bioactive properties of biodegradable materials in of the human factors and ergonomics society annual meeting:
Sage Publications, Los Angeles, CA, 1411–1415.
in situ scenarios [151] . Nevertheless, the body’s natural
immunomodulating responses still present significant 2. Granville-Chapman J, Jacobs N, Midwinter M, 2011, Pre-
obstacles in developing implantable materials and medical hospital haemostatic dressings: A systematic review. Injury,
devices, especially for safe and effective clinical use . 42: 447–459.
[82]
Fortunately, advances in the hemostatic mechanisms of 3. Du X, Wu L, Yan H, et al., Microchannelled alkylated
micro/nanostructures have provided strategies to resist chitosan sponge to treat noncompressible hemorrhages and
the foreign-body response. Novel elucidations will serve to facilitate wound healing. Nat Commun, 12: 4733.
develop novel strategies to further mitigate such negative 4. Zheng DW, Hong S, Xu L, et al., 2018, Hierarchical
responses in the future [149] . micro-/nanostructures from human hair for biomedical
applications. Adv Mater, 30: e1800836.
Acknowledgments 5. He J, Liang Y, Shi M, et al., 2020, Anti-oxidant electroactive and
Not applicable. antibacterial nanofibrous wound dressings based on poly(ε-
caprolactone)/quaternized chitosan-graft-polyaniline for full-
Funding thickness skin wound healing. J Chem Eng, 385: 123464.
6. Nouri-Goushki M, Angeloni L, Modaresifar K, et al., 2021,
This work was supported by the ‘Basic Science Research 3D-printed submicron patterns reveal the interrelation
Program’ through the ‘National Research Foundation between cell adhesion, cell mechanics, and osteogenesis.
of Korea’ funded by the Ministry of Education (NRF- ACS Appl Mater Interfaces, 13: 33767–33781.
2018R1A16A1A03025582, NRF- 2019R1D1A3A03103828,
and NRF- 2022R1I1A3063302). 7. Xie X, Li D, Chen Y, et al., 2021, Conjugate electrospun
3D gelatin nanofiber sponge for rapid hemostasis.
Conflict of interest Adv Healthc Mater, 10, e2100918.
8. Wang K, Dong R, Tang J, et al., 2021, Exosomes laden
The authors declare no conflicts of interest. self-healing injectable hydrogel enhances diabetic wound
healing via regulating macrophage polarization to accelerate
Author contributions angiogenesis. J Chem Eng, 430: 132664.
Conceptualization: Keya Ganguly, Maria Mercedes Espinal 9. Wang Z, Agrawal P, Zhang YS, 2021, Nanotechnologies
Investigation: Keya Ganguly, Maria Mercedes Espinal and nanomaterials in 3D (Bio)printing toward bone
Writing – original draft: Keya Ganguly, Maria Mercedes regeneration. Adv NanoBio Res, 1: 2100035.
Espinal 10. Sun X, Bai Y, Zhai H, et al., 2019, Devising micro/nano-
Writing – review & editing: Keya Ganguly, Sayan Deb Dutta, architectures in multi-channel nerve conduits towards a
Dinesh K. Patel, Tejal V. Patil, Rachmi Luthfikasari pro-regenerative matrix for the repair of spinal cord injury.
Funding acquisition: Ki-Taek Lim Acta Biomater, 86: 194–206.
Project administration: Ki-Taek Lim 11. Li M, Liang Y, Liang Y, et al., 2022, Injectable stretchable
Supervision: Ki-Taek Lim self-healing dual dynamic network hydrogel as adhesive
anti-oxidant wound dressing for photothermal clearance of
Ethics approval and consent to participate bacteria and promoting wound healing of MRSA infected
motion wounds. J Chem Eng, 427: 132039.
Not applicable.
12. Xie C, Ye J, Liang R, et al., 2021, Advanced strategies of
Consent for publication biomimetic tissue-engineered grafts for bone regeneration.
Adv Healthc Mater, 10: e2100408.
Not applicable.
13. Nam S, Mooney D, 2021, Polymeric tissue adhesives. Chem
Rev, 121:11336–11384.
Availability of data
14. Wan X, Liu Z, Li L, 2021, Manipulation of stem cells fates:
Not applicable. The master and multifaceted roles of biophysical cues of
biomaterials. Adv Funct Mater, 31: 2010626.
Volume 9 Issue 1 (2023)olume 9 Issue 1 (2023)
V 373 https://doi.org/10.18063/ijb.v9i1.648

