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International Journal of Bioprinting           Steam-sterilized and degradable FFF-printed PLA/PHA surgical guides


            there are different methods by which the surgical guide’s   cofunded by the European Funds for Regional Development
            accuracy can be assessed. The assessment of the post-  (EFRE) and the German state Rhineland-Palatinate.
            operative implant position requires either CBCT scan or an
            intraoral scan. The CBCT scan could be imprecise because   Conflict of interest
            of beam hardening effects, which can negatively impact   The authors declare that they have no competing interests.
            the matching of the image to the pre-operative planned
            position of the implant. Intraoral scan on the other side   Author contributions
            may be affected by the registration process itself, especially
            when reference points are scarce.                  Conceptualization: Matthias Gielisch, Christoph Boesing,
                                                                  Bilal Al-Nawas, Peer W. Kämmerer
              Furthermore, the length of the used implant could also   Data curation: Matthias Gielisch, Marc Krumpholtz
            have an effect on the measured deviation. For example, for   Investigation: Matthias Gielisch, Daniel G.E. Thiem, Marc
            the same deviation at implant base and the same angular   Krumpholtz, Peer W. Kämmerer
            deviation, a longer implant has a higher deviation at the apex   Methodology: Matthias Gielisch, Christoph Boesing, Marc
            than a shorter one. For various long implants, the implant   Krumpholtz, Bilal Al-Nawas, Peer W. Kämmerer
            length has no effect on the accuracy after static navigation,   Supervision: Bilal Al-Nawas, Peer W. Kämmerer
            while a long distance between the sleeve and the bone has a   Validation: Matthias Gielisch, Diana Heimes, Daniel G. E.
            negative effect . To the knowledge of the authors, no data   Thiem, Christoph Boesing, Marc Krumpholtz, Bilal
                       [36]
            comparing short implants versus longer implants regarding   Al-Nawas, Peer W. Kämmerer
            the accuracy after static navigation is available.  Visualization: Matthias Gielisch, Diana Heimes
              In this study, we used the sterilization protocol that is   Writing – original draft: Matthias Gielisch, Diana Heimes,
            regularly used in the sterilization department. The effect   Daniel G. E. Thiem, Peer W. Kämmerer
            of other protocols with longer or shorter cycles, higher or   Writing  –  review  &  editing: Matthias Gielisch, Diana
            lower temperatures, and other pressure settings was not   Heimes, Daniel G. E. Thiem, Christoph Boesing, Marc
            investigated in the present study. Using lower temperatures   Krumpholtz, Bilal Al-Nawas, Peer W. Kämmerer
            could result in less deformation, but the protocols with the
            lower temperatures require longer durations of sterilization   Ethics approval and consent to participate
            process, so the material changes are not necessarily lesser.  Not applicable.
              A question, regarding this topic, remains as to whether
            a  less  accurate  implantation  with  PLA/PHA  guides  can   Consent for publication
            be justified with the benefits of degradation or recycling   Not applicable.
            capabilities of the material, even if the existing materials
            without those capabilities can attain better results. This   Availability of data
            topic must be further studied and discussed.       Data  can  be  obtained  on reasonable  request from  the

            5. Conclusion                                      corresponding author.
            The  studied  PLA/PHA  printing  material  showed  high,   References
            significant deviations in angle and 3D accuracy at the   1.   Gibson I, David R, Stucker B, 2015, Additive Manufacturing
            implant base after steam sterilization in comparison to   Technologies: 3D Printing, Rapid Prototyping, and Direct
            non-sterile PLA/PHA guides  and  guides  printed  with   Digital Manufacturing. Berlin: Springer.
            MED610. However, short implants with a length of 5.5 mm      https://doi.org/10.1007/978-1-4939-2113-3
            could be placed with a sterilized PLA/PHA guide with a
            comparable accuracy as implants placed with guides made   2.   Goetze E, Gielisch M, Moergel M, et al., 2017, Accelerated
            of materials already used in clinical practice.       workflow for primary jaw reconstruction with microvascular
                                                                  fibula graft. 3D Print Med, 3: 3.
            Acknowledgments                                       https://doi.org/10.1186/s41205-017-0010-7

            None.                                              3.   Goetze E, Kämmerer PW, Al-Nawas B,  et  al., 2020,
                                                                  Integration of perforator vessels in CAD/CAM free fibula
            Funding                                               graft planning: A clinical feasibility study. J Maxillofac Oral

            The presented results are partially part of the ongoing   Surg, 19: 61–66.
            InnoProm-project “3D Biopolymer” (Grant No: 84003603)      https://doi.org/10.1007/s12663-019-01215-y


            Volume 9 Issue 2 (2023)                         84                      https://doi.org/10.18063/ijb.v9i2.655
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