Page 88 - IJB-9-2
P. 88

International Journal of Bioprinting           Steam-sterilized and degradable FFF-printed PLA/PHA surgical guides



            A                                                  Table 1. The means and standard deviations (SD) of the
                                                               measured variables.
                                                                Guide material   MED610          PLA/PHA
                                                                            Non‑sterile   Sterile    Non‑sterile   Sterile
                                                                              N = 5   N = 5    N = 5    N = 5
                                                               Angular deviation,  0.72 (0.55)  1.10 (0.77)  0.38 (0.53)  2.88 (0.75)
            B                                                  mean (SD)
                                                               3D deviation at   0.38 (0.09)  0.36 (0.17)  0.49 (0.21)  0.94 (0.23)
                                                               implant base,
                                                               mean (SD)
                                                               3D deviation at   0.42 (0.13)  0.42 (0.23)  0.50 (0.23)  1.04 (0.19)
                                                               implant apex,
                                                               mean (SD)
            C                                                  Highest values were seen in sterile PLA/PHA guides for angular
                                                               deviation, as well as 3D deviation at implant base and apex. PLA/PHA:
                                                               Polylactide/polyhydroxyalkanoate


                                                               Inaccuracy  in  implant  position  may  occur  because  of
                                                               asymmetric bone structure, limited experience of the
                                                                                                [22]
            D                                                  dentist, and limited mouth opening . Computer-
                                                               assisted implant surgery enables pre-surgical planning
                                                               of the future implant position along with the protection
                                                               of relevant anatomical structures and allows for a highly
                                                               precise  surgery.  There  are  different  ways  of  performing
                                                               guided implant surgery: While dynamic guiding may be
                                                               impractical for most dental practices due to high cost and
            Figure 4. Workflow of the deviation measurement. (A) Four-point   the complexity of the procedure, static surgical guidance is
            matching of planning model (blue) and model generated out of the post-  a commonly used method in daily practices.
            operative dataset (red). First step of fine tuning is done by a matching
            algorithm by the software manufacturer. (B) Fine tuning of the matching   A variety of methods for creating such 3D-printed
            with coronar, sagital, and axial view and 3D overview for control (blue:   surgical guides have evolved over time. FFF uses a melted
            planning model and yellow: matched post-operative model); (C) Since   thermoplastic extruded by the printer head, which is
            the position of the placed implant cannot be recognized from the software
            automatically, manual adjustment was carried out to superimpose the   continuously layered on a platform, while in the material
            red outlined model of the implant on the implant from the cone beam   jetting process, a carriage jets photopolymers onto a
            computed tomography scan. (D) Calculation of the deviations based on   surface, which are then cured with ultraviolet light .
                                                                                                       [21]
            the surgical plan (blue-colored implant) and the post-operative situation
            (red-colored implant) was done.                      The dimensional accuracy of such 3D models has been
                                                               found to be affected by several factors, such as quality of
            MED610 showed significant differences (P = 0.01, P < 0.01   diagnostic radiographic imaging and radiographic template,
            and  P  < 0.01). The same measurements for unsterilized   accuracy of digital cast produced by scanning, accuracy of
            guides, regardless of the material used, revealed no   surgical template and its stable fit on the supporting tissue,
            differences (Table 2).                             and surgeon’s execution of the planned surgery, and also
                                                               by process-specific factors, such as manufacturing process
            4. Discussion                                      itself, build orientation, number of objects being printed,
            The aim of this study was to compare the structural stability   types of sleeve inserts, and post-processing methods [21,22] .
            and accuracy of PLA/PHA, a biodegradable 3D printing   Several studies have been performed to analyze the effect
            material,  and  MED610,  a  material  jetting  material  for   of disinfection and sterilization procedures on dimensional
            medical applications, as surgical guides for short implants   changes of 3D-printed guides. These characteristics are
            with and without steam sterilization. The target variable   generally assessed using various software tools to compare
            was quantified by the deviation at the implant base and the   STL datasets. The assessment of the postoperative implant
            angle deviation.                                   position is another method to quantify the accuracy of the
              To achieve the best possible functional and esthetic   surgical  guide;  here  either  a  CBCT  scan  or  an  intraoral
            outcome,  optimal  dental  implant  placement  is  crucial.   scan is needed .
                                                                          [21]

            Volume 9 Issue 2 (2023)                         80                      https://doi.org/10.18063/ijb.v9i2.655
   83   84   85   86   87   88   89   90   91   92   93