Page 23 - IJB-9-4

International Journal of Bioprinting

RESEARCH ARTICLE
Hybrid solid mesh structure for electron beam

melting customized implant to treat bone cancer

Jong Woong Park 1,2,3† , Eunhyeok Seo , Haeum Park , Ye Chan Shin ,
2
5
4†
Hyun Guy Kang , Hyokyung Sung *, Im Doo Jung *
1
6
4
1 Orthopaedic Oncology Clinic, Center for Rare Cancers, National Cancer Center, Goyang 10408,
Republic of Korea
2 Surgical Oncology Branch, Division of Clinical Research, National Cancer Center, Goyang 10408,
Republic of Korea
3
Department of Cancer Control and Population Health, NCC-Graduate School of Cancer Science
and Policy, National Cancer Center, Goyang 10408, Republic of Korea
4 Department of Mechanical Engineering, Ulsan National Institute of Science and Technology,
UNIST-gil 50, Ulsan, 44919, Republic of Korea
5 Department of 3D Printing Materials, Korea Institute of Materials Science, Changwon, 51508,
Republic of Korea
6 Department of Materials Science and Engineering, Kookmin University, Seoul 02707, Republic of
Korea
(This article belongs to the Special Issue: Laser bioprinting technologies)

Abstract

Bone replacement implants manufactured by electron beam melting have been
† These authors contributed equally widely studied for use in bone tumor treatment. In this application, a hybrid structure
to this work. implant with a combination of solid and lattice structures guarantees strong
*Corresponding authors: adhesion between bone and soft tissues. This hybrid implant must exhibit adequate
Hyokyung Sung mechanical performance so as to satisfy the safety criteria considering repeated
(hyokyung@kookmin.ac.kr) weight loading during the patient’s lifetime. With a low volume of a clinical case,
Im Doo Jung various shape and volume combinations, including both solid and lattice structures,
(idjung@unist.ac.kr)
should be evaluated to provide guidelines for implant design. This study examined
Citation: Park JW, Seo E, Park H, the mechanical performance of the hybrid lattice by investigating two shapes of the
et al., 2023, Hybrid solid mesh
structure for electron beam melting hybrid implant and volume fractions of the solid and lattice structures, along with
customized implant to treat bone microstructural, mechanical, and computational analyses. These results demonstrate
cancer. Int J Bioprint, 9(4): 716. how hybrid implants may be designed to improve clinical outcomes by using patient-
https://doi.org/10.18063/ijb.716
specific orthopedic implants with optimized volume fraction of the lattice structure,
Received: November 03, 2022 allowing for effective enhancement of mechanical performance as well as optimized
Accepted: February 02, 2023
Published Online: March 21, 2023 design for bone cell ingrowth.
Copyright: © 2023 Author(s).
This is an Open Access article Keywords: 3D printing; Bone cancer; Titanium alloy implant; Electron beam melting;
distributed under the terms of the Fracture analysis
Creative Commons Attribution
License, permitting distribution
and reproduction in any medium,
provided the original work is
properly cited.
1. Introduction
Publisher’s Note: Whioce
Publishing remains neutral with The limb salvage surgery is one of the treatment processes for bone sarcoma that
regard to jurisdictional claims in resects bone tumors with wide margins and reconstructs bone and soft-tissue defects.
published maps and institutional
affiliations. Endoprosthesis and biological substitutes, such as bone allografts or recycled autografts,

Volume 9 Issue 4 (2023) 15 https://doi.org/10.18063/ijb.716