Page 20 - IJB-9-4

International Journal of Bioprinting Biomimetic 3D printed glioma model

improve the survival rate of neurons and synaptic growth Availability of data
in the bioprinted glioma in vitro 3D model. These results Not applicable.
are an indication of the two-way promotion relationship
between glioma cells and neurons around them in the References
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glioma cells. Cancer Biol Ther, 17(6):604–613.
The work was supported by the Program of the National 5. Wang C, Tong X, Yang F, 2014, Bioengineered 3D brain
Natural Science Foundation of China [52275291], tumor model to elucidate the effects of matrix stiffness on
[51675411], [81972359], the Fundamental Research Funds glioblastoma cell behavior using PEG-based hydrogels. Mol
for the Central Universities, and the Youth Innovation Pharm, 11(7):2115–2125.
Team of Shaanxi Universities.
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of glioma organoids. Cell Commun Signal, 19(1):1–13.
Conflict of interest
7. Zhang C, Jin M, Zhao J, et al., 2020, Organoid models of
The authors declare no conflict of interests. glioblastoma: Advances, applications and challenges. Am J
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Author contributions 8. De Witt Hamer PC, Van Tilborg AAG, Eijk PP, et al.,
Conceptualization: Ling Wang, Xinggang Mao, Na Pei, 2008, The genomic profile of human malignant glioma
Luge Bai is altered early in primary cell culture and preserved in
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Jiajia Zhou, Siqi Yao between glioblastoma stem cells and differentiated tumor
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Ethics approval and consent to participate 12. Yuan X, Curtin J, Xiong Y, et al., 2004, Isolation of cancer
stem cells from adult glioblastoma multiforme. Oncogene,
All animal experiments were approved and performed in 23(58):9392–9400.
accordance with the protocols approved by the Animal
Ethics Committee at Xi’an Jiaotong University (protocol 13. Mirab F, Kang YJ, Majd S, 2019, Preparation and
code 2022-15 and date of approval is March 1, 2022). characterization of size-controlled glioma spheroids using
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Volume 9 Issue 4 (2023) 12 https://doi.org/10.18063/ijb.715