Page 310 - IJB-9-4

International Journal of Bioprinting

RESEARCH ARTICLE
Biomechanical properties of 3D printable

material usable for synthetic personalized
healthy human aorta

Siyu Lin *, Georges Tarris , Chloe Bernard , Moundji Kafi , Paul M. Walker ,
3
2
1
3
1,4
Diana M. Marín-Castrillón , Camille Gobled , Arnaud Boucher , Benoit Presles ,
1
1
5
1
Marie Catherine Morgant , Alain Lalande , Olivier Bouchot 1,3
1,4
1,3
1 ImViA Laboratory, EA 7535, University of Burgundy, Dijon, France
2 Department of Pathology, University Hospital of Dijon, Dijon, France
3 Department of Cardio-Vascular and Thoracic Surgery, University Hospital of Dijon, Dijon, France
4 Department of Medical Imaging, University Hospital of Dijon, Dijon, France
5
ENNOIA Company, Besançon, France
Abstract
With the development of three-dimensional (3D) printing, 3D-printed products
have been widely used in medical fields, such as plastic surgery, orthopedics,
dentistry, etc. In cardiovascular research, 3D-printed models are becoming more
realistic in shape. However, from a biomechanical point of view, only a few studies
have explored printable materials that can represent the properties of the human
aorta. This study focuses on 3D-printed materials that might simulate the stiffness
of human aortic tissue. First, the biomechanical properties of a healthy human
aorta were defined and used as reference. The main objective of this study was to
*Corresponding author: identify 3D printable materials that possess similar properties to the human aorta.
Siyu Lin (siyu.lin@u-bourgogne.fr) Three synthetic materials, NinjaFlex (Fenner Inc., Manheim, USA), Filastic (Filastic
TM
©
Citation: Lin S, Tarris G, Bernard C, Inc., Jardim Paulistano, Brazil), and RGD450+TangoPlus (Stratasys Ltd. , Rehovot,
et al., 2023, Biomechanical Israel), were printed in different thicknesses. Uniaxial and biaxial tensile tests were
properties of 3D printable material
usable for synthetic personalized performed to compute several biomechanical properties, such as thickness, stress,
healthy human aorta. Int J Bioprint, strain, and stiffness. We found that with the mixed material RGD450+TangoPlus, it
9(4): 736. was possible to achieve a similar stiffness to healthy human aorta. Moreover, the
https://doi.org/10.18063/ijb.736
50-shore-hardness RGD450+TangoPlus had similar thickness and stiffness to the
Received: September 09, 2022 human aorta.
Accepted: January 27, 2023
Published Online: April 20, 2023
Copyright: © 2023 Author(s). Keywords: 3D printing; Biomechanical property; Human aorta; Tensile test
This is an Open Access article
distributed under the terms of the
Creative Commons Attribution
License, permitting distribution
and reproduction in any medium, 1. Introduction
provided the original work is
properly cited. Three-dimensional (3D) printing has been widely used in various fields. The
technology uses computational 3D imaging software to sort out tomographic data in
Publisher’s Note: Whioce
Publishing remains neutral with order to produce 3D reconstruction images. This information can be regenerated into
regard to jurisdictional claims in standard tessellation language (STL) files. In recent years, medical fields such as plastic
published maps and institutional surgery, orthopedics, dentistry, etc. have also begun to apply 3D printing [1-6] . The main
affiliations.

Volume 9 Issue 4 (2023) 302 https://doi.org/10.18063/ijb.736