Page 323 - IJB-9-4

International Journal of Bioprinting 3D printing in bone regeneration and bone repair

33 publications, including 31 research articles and 2 review of keywords was captured in VOSviewer figures. In these
articles, were searched before July 1, 2012. In order to figures, each node represents an item (such as co-cited
report the recent research progress in a timely manner and reference or keyword), with the node size representing the
accurately predict the trend of publication in the field of number of publications and color representing different
3DP for bone regeneration and repair, the beginning year years. The line thickness between nodes indicates the
was set as 2012. strength of the collaboration or co-citation relationship.
The publication information of the selected studies,
including the journal name, title, authors, keywords, 3. Results
institutions, country/region, publication date, total and
average number of citations, as well as the H-index, were 3.1. Global contribution to the field
downloaded and imported into Excel 2021 for analysis by Based on the search strategy (Figure 1), a total of 2,025
the authors (Z.Y. and H.L.). The database expiration date publications met the inclusion criteria and were used
was set to August 9, 2022. A bibliometric and visualized for analysis. The RRI in 3DP for bone regeneration and
analysis was performed using the following software: repair increased approximately linearly between 2012
GraphPad Prism 8, Origin 2021, VOSviewer 1.6.14 (Leiden and 2022, which is also reflected by the number of annual
University, Leiden, the Netherlands) , and CiteSpace publications increasing from 1 to over 500 in the given
[32]
6.1.2 . The sum and annual number of publications in timeframe (Figure 2A). In total, 72 countries/regions
[33]
the top 10 countries as well as the model fitting curves contributed publications to this research area. China
were calculated using Origin 2021. VOSviewer was used contributed the most papers (817, 40.346%), followed by
to analyze journals that were co-cited in more than 20 the United States of America (USA; 408, 20.148%), South
citations and the distribution of keywords with a minimum Korea (197, 9.728%), Germany (118, 5.827%), and England
number of occurrences of 20 as well as for citation analysis (117, 5.778%) (Figure 2B–C, Table 1). Furthermore, China
of documents with more than 25 citations. exhibited the highest increase in publication number
since 2012, with the volume of publications equivalent
2.2. Bibliometric analysis and visualization to the total number of publications from the remaining
The annual trend of publications and relative research 9 countries/regions (Figure 2D). A generalized additive
interest (RRI), defined by the number of publications in model showing the predicted number of publications by
a certain field divided by that in all fields per year, was year was also constructed (Figure 2E). According to this
depicted using the curve-fitting function of GraphPad time curve, the annual growth trend was in line with
2
Prism 8. A world map was constructed in accordance the fitting curve y = 59.867x – 120557.289 (R = 0.917),
with previous studies . The total publications in the top verifying a linearly increasing rate of annual publications
[34]
10 countries between 2012 and 2022 as well as the global in this area.
trend prediction were analyzed using Origin 2021. The
impact factor (IF) of journals was obtained from Journal 3.2. Distribution of countries/regions and
Citation Reports 2021. institutions contributing to the field
All publications that were included in this study originated
Country/region and institution collaboration analysis,
dual-map overlay of journals, author collaboration and from 72 countries and 1,967 institutions. The top 10
contributing countries/regions were distributed in Asia,
co-cited authors analysis, cluster detection of co-cited North America, and Western Europe (Table 1). Among
references and keywords, as well as analysis of references these, China and the USA accounted for over 60% of total
and keywords with intense citation bursts were all publications, far exceeding any other country/region. As
conducted using CiteSpace 6.1.2. In accordance with shown in Table 1, China had the highest number of total
a previous study, the parameters of CiteSpace used for citations at 19,817 and an H-index of 70, while the USA
analysis were as follows: link retaining factor (LRF = 3), had the second highest number of total citations and the
look back years (LBY = 5), e for top N (e = 1), time span highest average citation of 37.16. Although Italy and the
(2012–2022), years per slice (1), links (strength: cosine; Netherlands contributed to less than 8% of the total number
scope: within slices), selection criteria (g-index: k = 25), of publications, their average citation per publication
and minimum duration (MD = 2 for keywords; MD = 5 ranked second and third, respectively. The mapping of
for references) .
[30]
collaborations among countries/regions contributing to
The construction and visualization of bibliometric the field is shown by the connections among nodes, where
networks were performed using VOSviewer. the node size represents the total number of publications
Comprehensive information on (1) co-citation analysis of (Figure 3A). It is interesting to note that although China
journals and references as well as (2) co-occurrence analysis had the highest number of publications in the field, the

Volume 9 Issue 4 (2023) 315 https://doi.org/10.18063/ijb.737