Page 320 - IJB-9-4

International Journal of Bioprinting

RESEARCH ARTICLE
Research landscape of 3D printing in bone

regeneration and bone repair: A bibliometric and
visualized analysis from 2012 to 2022

Zhen Yang 1,2† , Hao Li 3,4,5† , Jianjing Lin , Dan Xing , Jiao Jiao Li , Elise M. Cribbin ,
7
7
6
1,2
Alice M. Kim , Zihao He , Hui Li , Weimin Guo *, Licheng Zhang *,
1,2
7
1,2
4,5
8
Jianhao Lin *
1,2
1 Arthritis Clinical and Research Center, Peking University People’s Hospital, Beijing 100044, China
2 Arthritis Institute, Peking University, Beijing 100044, China
3 School of Medicine, Nankai University, Tianjin 300071, China
4 Department of Orthopedics, Chinese PLA General Hospital, Beijing, China
5
National Clinical Research Center for Orthopedics, Sports Medicine and Rehabilitation, Beijing, China
6 Department of Sports Medicine and Rehabilitation, Peking University Shenzhen Hospital,
Shenzhen, China
7 School of Biomedical Engineering, Faculty of Engineering and IT, University of Technology Sydney,
Sydney, Australia
8 Department of Orthopaedic Surgery, Guangdong Provincial Key Laboratory of Orthopedics and
Traumatology, First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, 510080, China
† These authors contributed equally (This article belongs to the Special issue: Advances in the application of 3D printing in medicine and dentistry)
to this work.
*Corresponding authors: Abstract
Weimin Guo
(guowm5@mail.sysu.edu.cn) Three-dimensional printing (3DP) is a popular manufacturing technique with
Licheng Zhang versatile potential for materials processing in tissue engineering and regenerative
(zhanglcheng218@126.com)
Jianhao Lin medicine. In particular, the repair and regeneration of significant bone defects remain
(linjianhao@pkuph.edu.cn) as substantial clinical challenges that require biomaterial implants to maintain
mechanical strength and porosity, which may be realized using 3DP. The rapid
Citation: Yang Z, Li H, Lin J, et al.,
2023, Research landscape of 3D progress in 3DP development in the past decade warrants a bibliometric analysis
printing in bone regeneration and to gain insights into its applications in bone tissue engineering (BTE). Here, we
bone repair: A bibliometric and performed a comparative study using bibliometric methods for 3DP in bone repair
visualized analysis from 2012 to
2022. Int J Bioprint, 9(4): 737. and regeneration. A total of 2,025 articles were included, and the results showed an
https://doi.org/10.18063/ijb.737 increase in the number of publications and relative research interest on 3DP annually
Received: November 06, 2022 worldwide. China was the leader in international cooperation in this field and also the
Accepted: January 24, 2023 largest contributor to the number of citations. The majority of articles in this field were
Published Online: April 26, 2023 published in the journal Biofabrication. Chen Y was the author who made the highest
Copyright: © 2023 Author(s). contribution to the included studies. The keywords included in the publications were
This is an Open Access article mainly related to BTE and regenerative medicine (including “3DP techniques,” “3DP
distributed under the terms of the materials,” “bone regeneration strategies,” and “bone disease therapeutics”) for bone
Creative Commons Attribution
License, permitting distribution regeneration and repair. This bibliometric and visualized analysis provides significant
and reproduction in any medium, insights into the historical development of 3DP in BTE from 2012 to 2022, which will
provided the original work is be beneficial for scientists to conduct further investigations into this dynamic field.
properly cited.
Publisher’s Note: Whioce
Publishing remains neutral with Keywords: Bibliometrics; 3D printing; Bone regeneration; Bone repair; Tissue
regard to jurisdictional claims in engineering; Visualization research
published maps and institutional
affiliations.

Volume 9 Issue 4 (2023) 312 https://doi.org/10.18063/ijb.737