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International Journal of Bioprinting 3D printing in bone regeneration and bone repair

Figure 1. Flowchart showing the article selection process. Abbreviations: SCI, Science Citation Index; WoSCC, Web of Science Core Collection.

correlating materials and structural design aspects of 3DP (SCI) Expanded database of Clarivate Analytics’ Web
with biological response after implantation . of Science Core Collection (WoSCC). The included
[19]
studies were then analyzed using bibliometric techniques
Despite rapid and dynamic developments in the field
of 3DP for BTE, a comprehensive and meaningful analysis and visual analytics tools in accordance with previous
[29,30]
of publication trends in this research area has not been studies . The search date was set between July 1, 2012
performed. This demonstrates the need for a more in- and July 1, 2022, and the following search formula was
depth understanding and summarization of the current used: TS = (3D bioprinting OR 3D printing OR 3D printed
frontiers in 3DP for bone repair and regeneration in OR 3D print OR three dimensional bioprinting OR three
preparation for more large-scale clinical implementation. dimensional printing OR three dimensional printed OR
Bibliometrics is a quantitative analysis using mathematical three dimensional print) AND TS = (bone regeneration
[28]
and statistical methods to analyze published research . It OR bone repair). The inclusion criteria were as follows:
provides objective scientific indicators for researchers to (1) publications that focused on the theme of 3DP in bone
track quantitative changes and distributions of published regeneration and repair; (2) original research or review
literature. In this study, we comprehensively analyze the articles; and (3) studies that were written in English.
quantity and quality of 3DP studies in BTE research, The exclusion criteria were as follows: (1) publications
presenting a summary of the current status of this research that were not related to using 3DP in bone regeneration
area and a prediction of the most relevant keywords, which and repair; (2) meeting abstracts, proceedings papers,
will assist researchers in identifying the imminent trends book chapters, editorials, letters, news, etc. (Figure 1).
and frontiers in this rapidly evolving field. All publications were analyzed by two reviewers (Z.Y.
and H.L.), and any potentially irrelevant studies were
identified and manually filtered and discussed with the
2. Materials and methods experienced corresponding authors to determine whether
2.1. Data acquisition and search strategies they should be included or excluded from the analysis.
Papers relating to research on 3DP in bone regeneration In 2011, Fedorovich et al. have reported the progress of
and repair were collated from the Science Citation Index organ printing in bone regeneration . Additionally, only
[31]
Volume 9 Issue 4 (2023) 314 https://doi.org/10.18063/ijb.737