Page 89 - IJB-9-6
P. 89
International Journal of Bioprinting Review of 3D bioprinted organoids
References [49,50,74] [51,61,75] [49,60,61,63,64] [61,76,77] [52,78] [79,80]
Bioprinted stem cells or organoids Mesenchymal stem cells (MSC) Bladder tumor organoids Human adipose stem cells Human embryonic stem cells Salivary glands organoids
Low resolution, 7 mm–210 µm The movement of the print head interferes with the droplet ejection and is not suitable for high-viscosity bioinks. Difficult to print complex structures and cell viability may be affected in the long term after printing, making it unsuitable for precise bioprinting applications The size of the nozzle hole limits the printing of bioinks within a specific viscosity range (1 to The cytotoxici
Drawbacks 200 mPa/s). effects on cells.
Enables the construction of layered tubular structures with adjustable biological/mechanical properties, with cell viability dependent on extrusion speed and nozzle diameter High resolution (~37 µm) and cell viability (>90%), high printing speed With a better resolution of 2–5 µm, cell viability >90%, suitable for printing high-viscosity Accurate cell localization, high cell survival rate Cell vitality >90%, reasonable spa
Table 2. More 3D bioprinting for stem cell or organoid bioprinting
Benefits bioinks >86%, fast printing speed
Basic principle One of EBB technologies, concentric nozzles are stacked to form coaxial nozzles for printing a variety of bioinks. One of the DBB technologies, bioinks are ejected in droplet form by force generated by sound waves. One of the DBB technologies that use a high-voltage-driven electric field to pull the bioink out of the nozzle hole in the form of a droplet A DBB technology in which a microvalve controls the op
3D bioprinting technology Coaxial bioprinting Acoustic bioprinting Electrohydrodynamic jetting (EHDJ) bioprinting Microvalve bioprinting Magnetic bioprinting
Volume 9 Issue 6 (2023) 81 https://doi.org/10.36922/ijb.0112

