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Journal of Clinical and
Basic Psychosomatics Melatonin for dementia therapy

19: 157–169. 8: 228–242.
https://doi.org/10.1016/S1474-4422(19)30153-X https://doi.org/10.2174/157015910792246155
7. Olney NT, Spina S, Miller BL, 2017, Frontotemporal 18. Zhang HM, Zhang Y, 2014, Melatonin: A well-documented
dementia. Neurol Clin, 35: 339–374. antioxidant with conditional pro-oxidant actions. J Pineal
Res, 57: 131–146.
https://doi.org/10.1016/j.ncl.2017.01.008
https://doi.org/10.1111/jpi.12162
8. Schmidt MF, Gan ZY, Komander D, et al., 2021, Ubiquitin
signalling in neurodegeneration: Mechanisms and 19. Feng Z, Chang Y, Cheng Y, et al., 2004, Melatonin alleviates
therapeutic opportunities. Cell Death Differ, 28: 570–590. behavioral deficits associated with apoptosis and cholinergic
https://doi.org/10.1038/s41418-020-00706-7 system dysfunction in the APP 695 transgenic mouse model
of Alzheimer’s disease. J Pineal Res, 37: 129–136.
9. Shi L, Chen SJ, Ma MY, et al., 2018, Sleep disturbances
increase the risk of dementia: A systematic review and meta- https://doi.org/10.1111/j.1600-079X.2004.00144.x
analysis. Sleep Med Rev, 40: 4–16. 20. Iwashita H, Matsumoto Y, Maruyama Y, et al., 2021, The
https://doi.org/10.1016/j.smrv.2017.06.010 melatonin metabolite N1-acetyl-5-methoxykynuramine
facilitates long-term object memory in young and aging
10. Fan R, Peng X, Xie L, et al., 2022, Importance of Bmal1 in mice. J Pineal Res, 70: e12703.
Alzheimer’s disease and associated aging-related diseases:
Mechanisms and interventions. Aging Cell, 21: e13704. https://doi.org/10.1111/jpi.12703
https://doi.org/10.1111/acel.13704 21. Sano M, Iwashita H, Hattori A, et al., 2022, Melatonin
enhances object recognition memory through melatonin
11. Reppert SM, Godson C, Mahle CD, et al., 1995, Molecular MT1 and MT2 receptor-mediated and non-receptor-
characterization of a second melatonin receptor expressed mediated mechanisms in male mice. J Behav Brain Sci,
in human retina and brain: The Mel1b melatonin receptor. 12: 640–657.
Proc Natl Acad Sci U S A, 92: 8734–8738.
https://doi.org/10.4236/jbbs.2022.1212038
https://doi.org/10.1073/pnas.92.19.8734
22. Galano A, Tan DX, Reiter RJ, 2013, On the free radical
12. Pandi-Perumal SR, Trakht I, Srinivasan V, et al., 2008, scavenging activities of melatonin’s metabolites, AFMK and
Physiological effects of melatonin: Role of melatonin AMK. J Pineal Res, 54: 245–257.
receptors and signal transduction pathways. Prog Neurobiol,
85: 335–353. https://doi.org/10.1111/jpi.12010
https://doi.org/10.1016/j.pneurobio.2008.04.001 23. Rudnitskaya EA, Maksimova KY, Muraleva NA, et al., 2015,
Beneficial effects of melatonin in a rat model of sporadic
13. Alghamdi BS, 2018, The neuroprotective role of melatonin Alzheimer’s disease. Biogerontology, 16: 303–316.
in neurological disorders. J Neurosci Res, 96: 1136–1149.
https://doi.org/10.1007/s10522-014-9547-7
https://doi.org/10.1002/jnr.24220
24. Gong YH, Hua N, Zang X, et al., 2018, Melatonin ameliorates
14. Kwon KJ, Kim HJ, Shin CY, et al., 2010, Melatonin potentiates aβ1-42 -induced Alzheimer’s cognitive deficits in mouse
the neuroprotective properties of resveratrol against beta- model. J Pharm Pharmacol, 70: 70–80.
amyloid-induced neurodegeneration by modulating AMP-
activated protein kinase pathways. J Clin Neurol, 6: 127–137. https://doi.org/10.1111/jphp.12830
https://doi.org/10.3988/jcn.2010.6.3.127 25. Muhammad T, Ali T, Ikram M, et al., 2019, Melatonin
rescue oxidative stress-mediated neuroinflammation/
15. Bonnefont-Rousselot D, Collin F, 2010, Melatonin: Action neurodegeneration and memory impairment in
as antioxidant and potential applications in human disease scopolamine-induced amnesia mice model. J Neuroimmune
and aging. Toxicology, 278: 55–67.
Pharmacol, 14: 278–294.
https://doi.org/10.1016/j.tox.2010.04.008
https://doi.org/10.1007/s11481-018-9824-3
16. Das A, McDowell M, Pava MJ, et al., 2010, The inhibition 26. Barchas J, DaCosta F, Spector S, 1967, Acute pharmacology
of apoptosis by melatonin in VSC4.1 motoneurons exposed
to oxidative stress, glutamate excitotoxicity, or TNF-alpha of melatonin. Nature, 214: 919–920.
toxicity involves membrane melatonin receptors. J Pineal https://doi.org/10.1038/214919a0
Res, 48: 157–169.
27. Nickkholgh A, Schneider H, Sobirey M, et al., 2011, The
https://doi.org/10.1111/j.1600-079X.2009.00739.x use of high-dose melatonin in liver resection is safe: First
clinical experience. J Pineal Res, 50: 381–388.
17. Esposito E, Cuzzocrea S, 2010, Antiinflammatory activity of
melatonin in central nervous system. Curr Neuropharmacol, https://doi.org/10.1111/j.1600-079X.2011.00854.x

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