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130                       Abtahi et al. | Journal of Clinical and Translational Research 2024; 10(2): 119-140
                                                          Appendix


        Table A1. Search strategies for each database
        Database Search strategies                                                                     Number of studies
        PubMed  ((“Triage”[Mesh]) OR (“Triage”[Title/Abstract]) OR (“Triages”[Title/Abstract]) OR (“patient classification”[Title/Abstract])   118
                OR (“disease severity”[Title/Abstract]) OR (“disease severity scale”[Title/Abstract])) AND ((“Forecasting”[Mesh]) OR
                (“Forecasting”[Title/Abstract]) OR (“predict*”[Title/Abstract]) OR (“Prediction”[Title/Abstract]) OR (“scoring system”[Title/
                Abstract]) OR (“scoring”[Title/Abstract]) OR (“scale”[Title/Abstract])) AND ((“Care Unit, Intensive”[Title/Abstract]) OR (“Care
                Units, Intensive”[Title/Abstract]) OR (“Intensive Care Unit”[Title/Abstract]) OR (“Unit, Intensive Care”[Title/Abstract]) OR
                (“Disease Severity”[Title/Abstract]) OR (“Units, Intensive Care”[Title/Abstract]) OR (“Intensive Care Units”[Mesh])) AND ((“severe
                acute respiratory syndrome coronavirus 2” [Supplementary Concept]) OR (“COVID-19”[Title/Abstract]) OR (“SARS-CoV-2”[Title/
                Abstract]) OR (“2019 novel coronavirus”[Title/Abstract]) OR (“2019-nCoV”[Title/Abstract]) OR (“Wuhan coronavirus”[Title/
                Abstract]) OR (“novel coronavirus”[Title/Abstract]))
        Scopus  ( ( ( TITLE-ABS-KEY ( triage ) OR TITLE-ABS-KEY ( “patient classification” ) OR TITLE-ABS-KEY ( triages ) ) ) OR ( (   116
                TITLE-ABS-KEY ( “disease severity” ) OR TITLE-ABS-KEY ( “disease severity scale” ) ) ) ) AND ( ( TITLE-ABS-KEY (
                forecast* ) OR TITLE-ABS-KEY ( predict* ) OR TITLE-ABS-KEY ( prediction ) OR TITLE-ABS-KEY ( “scoring system”
                ) OR TITLE-ABS-KEY ( scoring ) OR TITLE-ABS-KEY ( scale ) ) ) AND ( ( TITLE-ABS-KEY ( “Care Unit, Intensive” )
                OR TITLE-ABS-KEY ( “Care Units, Intensive” ) OR TITLE-ABS-KEY ( “Intensive Care Unit” ) OR TITLE-ABS-KEY (
                “Unit, Intensive Care” ) OR TITLE-ABS-KEY ( “Units, Intensive Care” ) OR TITLE-ABS-KEY ( “Intensive Care Units” ) ) )
                AND ( ( TITLE-ABS-KEY ( “severe acute respiratory syndrome coronavirus 2” ) OR TITLE-ABS-KEY ( “COVID-19” ) OR
                TITLE-ABS-KEY ( “SARS-CoV-2” ) OR TITLE-ABS-KEY ( “2019 novel coronavirus” ) OR TITLE-ABS-KEY ( “2019-nCoV” )
                OR TITLE-ABS-KEY (“Wuhan coronavirus”) OR TITLE-ABS-KEY (“novel coronavirus”) ) )
        Web of   1. TS = (“Triage”) OR (“Triages”) OR (“patient classification”) OR (“disease severity”) OR (“disease severity scale”) From 2010 to   44
        Science  2020
                2. TS = (“Intensive Care Unit”) OR (“Care Unit, Intensive”) OR (“Intensive Care unit”) OR (“Unit, Intensive Care”) OR (“Units,
                Intensive Care”) OR (“Care Units, Intensive”) OR (“Intensive Care Units”)
                3. TS = (“severe acute respiratory syndrome coronavirus 2”) OR (“COVID-19”) OR (“SARS-CoV-2”) OR (“2019 novel coronavirus”)
                OR (“2019-nCoV”) OR (“Wuhan coronavirus”) OR (“novel coronavirus”) OR (“coronavirus”)
                Total=1 AND 2 AND 3


        Table A2. The contributing factors in clinical decision-making towards the length of hospital stay of COVID-19 patients
        Factors           Data set           Definition                                        CVR   CVR assessment
                                                                                                     (critical, essential, or
                                                                                                     rejected)
        Demographics and   Age               Age refers to the patient’s age based on the year.  0.4  Essential
        medical history   Sex                Sex refers to the gender of the patient.           −0.4  Rejected
                          BMI or obesity     BMI is a measure of body fat based on height and weight that applies to   0.4  Essential
                                             adult men and women.
                          History of diabetes   Diabetes mellitus is a metabolic disorder characterized by elevated blood   0.6  Essential
                          mellitus           sugar levels over a long period [48].
                          History of cancer or   Cancer is the abnormal growth of cells. The term malignancy refers to the   1  Critical
                          malignancy         presence of cancerous cells that can spread to other sites in the body [49,50].
                          CVD                CVD is any disease of the heart or any disorder associated with blood   0.8  Critical
                                             vessels [51].
                          History of renal function   CKD is the presence of kidney damage or an eGFR of <60 mL/min per   0.8  Critical
                          impairment or CKD  1.73 m  for more than two months [52].
                                                 2
                          History of respiratory   The most common respiratory diseases include COPD, asthma, pneumonia,   0.8  Critical
                          disease            pulmonary fibrosis, and lung cancer [53].
                          History of liver disease  Liver/hepatic disease is a type of damage to or disease of the liver that can   0.6  Essential
                                             be chronic or acute [54].
                          History of autoimmune   An autoimmune disease refers to any condition in which the immune system   0.6  Essential
                          disease            mistakenly attacks the body [55].
                          History of         Immunosuppressive drugs are a type of drug that suppresses or reduces the   0.8  Critical
                          immunosuppressive drug use strength of the body’s immune system [56].
                          History of hypertension  Hypertension refers to high blood pressure, which increases the risk of heart   0.2  Essential
                                             disease, stroke, and sometimes death [57].
                          Other chronic conditions   Comorbidity is defined as the concurrence of more than one disorder in an   0  Essential
                          or co-morbidity    individual [58].
                                                                                                              (Cont’d...)
                                                DOI: https://doi.org/10.36922/jctr.22.00226
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