Page 62 - JCTR-11-1

Journal of Clinical and

Translational Research

ORIGINAL ARTICLE
Prevalence and risk factors of osteoporosis in

diabetic individuals above 50 years of age at a
tertiary care hospital: An observational study

2
Sujata Devi 1 , Suchanda Sahu * , Deenadayalan Subhiksha 3 ,
4
Kishore Kumar Behera , Nibedita Priyadarsini 5 , Anupam Dey 1 ,
Debananda Sahoo 1 , and Arpita Dash 1
1 Department of General Medicine, All India Institute of Medical Sciences, Bhubaneswar, Odisha,
India
2 Department of Biochemistry, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India
3 All India Institute of Medical Sciences, Bhubaneswar, Odisha, India
4 Department of Endocrinology, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India
5 Department of Physiology, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India

Abstract
*Corresponding author: Background: Diabetes mellitus and osteoporosis coexist in the elderly population.
Suchanda Sahu
(biochem_suchanda@ However, there is no conclusive evidence as to whether diabetes affects the progression
aiimsbhubaneswar.edu.in) of osteoporosis in this population. In addition, diabetes-associated systemic
Citation: Devi S, Sahu S, Subhiksha D, complications may also contribute to an increased risk of fracture. Aim: To determine the
et al. Prevalence and risk factors of prevalence and risk factors of osteoporosis in diabetic individuals above 50 years of age
osteoporosis in diabetic individuals and to estimate the burden of the disease in males and females. Methods: A hospital-
above 50 years of age at a tertiary
care hospital: An observational study. based cross-sectional, and observational study was conducted in the Department of
J Clin Transl Res. 2025;11(1):56-65. General Medicine, All India Institute of Medical Sciences, Bhubaneswar (AIIMS). A total
doi: 10.36922/jctr.24.00062 of 203 diabetic individuals above 50 years of age were recruited in the study, and their
Received: September 17, 2024 bone mineral density (BMD) was evaluated using a dual-energy X-ray absorptiometry
scan. Other clinical and biochemical parameters were also assessed. A comparison was
1st revised: October 20, 2024
conducted among males and females and the three categories of BMD. Results: In
2nd revised: November 4, 2024 our study setting, the overall prevalence of osteoporosis in diabetic individuals above
Accepted: November 27, 2024 50 years of age was 40.89%. The prevalence was higher in females (56.5%) compared
to males (26%). A higher proportion of individuals (51.6%) in the 71–80 years age
Published online: February 24,
2025 group had osteoporosis. Increasing age and the duration of diabetes and menopause
(in females) were the significant risk factors, along with serum creatinine and glycated
Copyright: © 2025 Author(s).
This is an open-access article hemoglobin. Conclusion: As there is a high prevalence of osteoporosis among
distributed under the terms of the diabetics, screening by assessing the BMD must be done in the elderly population to
Creative Commons AttributionNon- predict the fracture risk (FRAX score), implement appropriate preventive measures,
Commercial 4.0 International (CC
BY-NC 4.0), which permits all and initiate treatment. Relevance for patients: Based on our findings, patients with
non-commercial use, distribution, diabetes mellitus are more prone to developing osteoporosis, which in turn increases
and reproduction in any medium, their likelihood to fracture development. In order to prevent further morbidity,
provided the original work is
properly cited. diabetics need special care for maintaining their health through the early detection
and prevention of such events.
Publisher’s Note: AccScience
Publishing remains neutral with
regard to jurisdictional claims in
published maps and institutional Keywords: Bone mineral density; T-score; FRAX score; Type 2 diabetes mellitus; Fracture
affiliations risk

Volume 11 Issue 1 (2025) 56 doi: 10.36922/jctr.24.00062