Page 69 - JCTR-11-1

Journal of Clinical and
Translational Research Osteoporosis risk factors in diabetics

setting is 40.89%. The prevalence is higher in females (56.5%) IEC/AIIMS BBSR/STS/2022-23/09, dated November
compared to males (26%). The proportion of pre-menopausal 23, 2023) and informed written consent from each study
women with osteoporosis was found to be 14.2%. A higher participant.
proportion of individuals (51.6%) in the 71–80 years’ age
group had osteoporosis. Anthropometric measurements Consent for publication
(BMI and WHR), HbA1C, and serum creatinine displayed Informed written consent was obtained from the patients
a significantly positive correlation with T-scores. Age and who were recruited into the study.
menopausal duration (in females) exhibited a significantly
negative correlation with the T-scores; increasing age and Data availability
menopausal duration (in females) are potential risk factors Data prepared from the patients’ medical and laboratory
for osteoporosis in our study population. Other factors (i.e., records are not available publicly. However, on reasonable
duration of diabetes, serum urea, serum calcium, Vitamin request, it can be provided.
D, urine ACR, and TSH levels) do not have any significant
association with the T-scores. Similar to the normal References
population, increasing age and menopause are significant
risk factors in diabetic individuals as well. Moreover, the 1. Misra A, Gopalan H, Jayawardena R, et al. Diabetes in
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and osteoporosis, and offered preventive, therapeutic, and shef.ac.uk/frax/pdfs/who_technical_report.pdf [Last
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Acknowledgments of osteoporosis. Eur J Rheumatol. 2017;4(1):46-56.
The authors are grateful for the support of AIIMS in doi: 10.5152/eurjrheum.2016.16011
conducting the investigations for the present study.
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The authors declare that no funds, grants, or other support doi: 10.1136/jirs.11.4.152
were received for the conduct of this study or in preparation
of this manuscript. 5. Babhulkar S, Seth S. Prevalence of osteoporosis in India: An
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Conflict of interest 362-368.

The authors declare that there is no financial or non- doi: 10.18203/issn.2455-4510
financial interest in the present study. 6. Chinese Medical Association. Guideline for primary care
of primary osteoporosis (2019). Chin J Gen Pr. 2020;19(4):
Author contributions 304-315.
Conceptualization: Sujata Devi, Deenadayalan Subhiksha doi: 10.3760/cma.j.issn.1674-6397.2020.04.001
Investigation: All authors 7. Wongdee K, Charoenphandhu N. Osteoporosis in diabetes
Writing - original draft: Sujata Devi, Suchanda Sahu, mellitus: Possible cellular and molecular mechanisms. World
Deenadayalan Subhiksha J Diabetes. 2011;2(3):41-48.
Writing - review & editing: Kishore Kumar Behera, Nibedita
Priyadarsini, Anupam Dey, Debananda Sahoo, Arpita doi: 10.4239/wjd.v2.i3.41
Dash 8. Adil C, Aydın T, Taşpınar Ö, et al. Bone mineral density
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The present study was conducted after obtaining approval doi: 10.1589/jpts.27.179
from the Institution Ethics Committee (approval number: 9. Xu L, Cheng M, Liu X, Shan P, Gao H. Bone mineral density

Volume 11 Issue 1 (2025) 63 doi: 10.36922/jctr.24.00062