Page 23 - JCTR-9-4

Marchand et al. | Journal of Clinical and Translational Research 2023; 9(4): 236-245 239

Main findings Showed a significant increase in live birth rate and implantation rates in women who received the fat emulsion infusion after IVF/ICSI There was an improvement in the pregnancy rate among women with unexplained RIF who received the fat emulsion therapy; however, this improvement did not reach statistical significance. Fat emulsion therapy did not increase chemical pregnancy rates. However, live birth

Male 13 11 39 45 NA NA

Infertility causes Unexplained PCOS 19 6 18 3 10 3 10 5 NA NA NA NA

Tubal 13 21 5 2 NA NA

Number of embryos transferred, mean±SD 2.09±1.1 2.48±1.07 1.8±0.54 1.9±0.51 2.5±0.5 2.6±0.5

Number of oocytes retrieved, mean±SD 5.96±3.45 4.62±1.99 NA NA 8.5±2.8 8.8±2.4

HCG dose 250 μg rHCG 10,000 IU 10,000 IU

Gn type rFSH rFSH/ HMG HMG

GnRH protocol Agonist/ Antagonist Long antagonist Long agonist

Body mass GnRH analogue index, mean±SD Leuprolide 4.06±3.12 acetate/ Cetrorelix 24.61±3.32 Cetrorelix 28.30±4.66 28.30±4.66 Triptorelin 22.6±2.6 acetate 22.9±2.2

Age (year), Sample mean±SD size 31.64±3.96 52 32.12±3.50 50 35.32±4.23 71 35.21±4.77 71 35.5±3.7 144 36±3.7 152

Table 1. Summary of the included studies Country Study arms India Fat emulsion group (Two doses of 4 mL of 20% fat emulsion in normal saline of 250 mL; 1 dose at oocyte recovery, 1 dose on day of embryo transfer) Control group (normal saline) Saudi Fat emulsion Arabia group (Two doses 20% 20% fat emulsion 100 mL diluted in 500 mL normal saline; 1 dose on day of embryo transfer, 1 dose on day of pregnancy test) Control gro

Singh et al.
Al-Zebeidi
(2019)[27]
(2019)[25]
Dakhly
Study
et al.
DOI: http://dx.doi.org/10.18053/jctres.09.202304.23-00060 et al. (2016) [29]