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Microbes & Immunity Klebsiella pneumoniae diagnosed by NGS

culture-negative Kp liver abscess not only improves the of Hong Kong–Shenzhen Hospital ([2022]120), and
timeliness and accuracy of diagnosis but also facilitates written informed consent was obtained prior to patients’
appropriate antibiotic therapy, thereby improving patient participation in this project.
outcomes and reducing morbidity associated with this
potentially severe infection. Consent for publication
Written informed content was obtained from the patients
Acknowledgments for the publication of this case report.
The authors are grateful to the staff at the Department of
Infectious Diseases and Microbiology, The University of Availability of data
Hong Kong–Shenzhen Hospital for their technical support The data that support the findings of this study are available
and assistance. from the corresponding author, Patrick C.Y. Woo.
Funding References

This work was partly supported by the Sanming Project of 1. Johannsen EC, Sifri CD, Madoff LC. Pyogenic liver abscesses.
Medicine in Shenzhen (grant number SZSM201911014) Infect Dis Clin North Am. 2000;14(3):547-563, vii.
and the Feature Areas Research Center Program within doi: 10.1016/s0891-5520(05)70120-3
the framework of the Higher Education Sprout Project by
the Ministry of Education in Taiwan (grant number MOE- 2. Rahimian J, Wilson T, Oram V, Holzman RS. Pyogenic liver
113-S-0023-A). abscess: Recent trends in etiology and mortality. Clin Infect
Dis. 2004;39(11):1654-1659.
Conflict of interest doi: 10.1086/425616
Patrick C. Y. Woo has provided scientific advisory/ 3. Jin S, Zhang Y, Zhao L, et al. Klebsiella pneumoniae related
laboratory services for Gilead Sciences, Incorporated; rare multi-site infections: A case series. Microbes Immunity.
International Health Management Associates, 2024;1(1):2600.
Incorporated; Merck and Corporation, Incorporated; and doi: 10.36922/mi.2600
Micología Molecular S.L. and Pfizer, Incorporated. Patrick 4. Wang TK, Wong SS, Woo PC. Two cases of pyomyositis
C. Y. Woo is also an Editorial Board Member of this caused by Klebsiella pneumoniae and review of the literature.
journal, but was not in any way involved in the editorial Eur J Clin Microbiol Infect Dis. 2001;20(8):576-580.
and peer-review process conducted for this paper, directly doi: 10.1007/s100960100556
or indirectly. Separately, other authors declared that they
have no known competing financial interests or personal 5. Lee CC, Chen CY, Chen FH, Zimmerman RA, Hsiao HS. Septic
relationships that could have influenced the work reported metastatic endophthalmitis from Klebsiella pneumoniae
in this paper. The funding sources had no role in study liver abscess: CT and MR imaging characteristics--report of
design, data collection, analysis, interpretation, or writing three cases. Radiology. 1998;207(2):411-416.
of the report. doi: 10.1148/radiology.207.2.9577489

Author contributions 6. Giorgio A, Tarantino L, Mariniello N, et al. Pyogenic liver
abscesses: 13 years of experience in percutaneous needle
Conceptualization: Fanfan Xing, Susanna K. P. Lau, Patrick aspiration with US guidance. Radiology. 1995;195(1):122-124.
C. Y. Woo doi: 10.1148/radiology.195.1.7892451
Formal analysis: Fanfan Xing, Susanna K. P. Lau, Patrick 7. Law ST, Li KK. Is pyogenic liver abscess associated with
C. Y. Woo recurrent pyogenic cholangitis a distinct clinical entity? A
Investigation: Chaowen Deng, Zhendong Luo, Jing Chen, retrospective analysis over a 10-year period in a regional
Simon K. F. Lo hospital. Eur J Gastroenterol Hepatol. 2011;23(9):770-777.
Methodology: Fanfan Xing, Simon K. F. Lo, Susanna K. P. doi: 10.1097/MEG.0b013e328348cb9c
Lau, Patrick C. Y. Woo
Writing – original draft: Fanfan Xing, Patrick C. Y. Woo 8. Yellin AE, Donovan AJ. Biliary lithiasis and helminthiasis.
Writing – review & editing: All authors Am J Surg. 1981;142(1):128-136.
doi: 10.1016/s0002-9610(81)80022-0
Ethics approval and consent to participate
9. Kwan KEL, Shelat VG, Tan CH. Recurrent pyogenic
Ethics approval for this retrospective study was endorsed cholangitis: A review of imaging findings and clinical
by the Institutional Review Board of The University management. Abdom Radiol (NY). 2017;42(1):46-56.

Volume 1 Issue 2 (2024) 98 doi: 10.36922/mi.4636