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Materials Science in Additive Manufacturing                      MAM for orthopedic bone plates: An overview



            two technologies: DED and PBF. Their market presence   evolution, especially in terms of their constitutive
            is substantial, with DED accounting for 16% and PBF a   materials. Conventionally, these materials are grouped
            dominant 54% of the 2020 market share .            into metals, bioceramics, and polymers . Metals, due to
                                           [31]
                                                                                               [52]
              The DED and PBF techniques, as depicted in Table 1,   their robust fixation capabilities and their resilience against
            have distinct methodologies and parameters. DED stands   daily  mechanical  loads,  particularly  in  long  bones,  have
            out for its adaptability, offering a range of feedstock   become the primary choice for bone plates. For a detailed
            options, including powders and wires. Moreover, its   comparison of these metallic materials in orthopedic
            versatility extends to energy sources, encompassing lasers,   contexts, refer to Table 2.
            electric arcs, and electron beams. This flexibility results   Initially, vanadium steel was the preferred material for
            in accelerated printing speeds, but often at the expense of   orthopedic implants. However, its limitations, particularly
            finer layer resolution.                            its subpar corrosion resistance and inadequate load-
              PBF, in contrast, is distinguished by its precision. While   bearing capacity, led to a search for better alternatives .
                                                                                                           [17]
            it primarily utilizes powders and has a more constrained   This search culminated in the adoption of stainless steel
            set of energy sources, it excels in delivering superior layer   (316L SS) and titanium alloy (Ti-6Al-4V). Characterized
            resolutions. A  noteworthy advantage of PBF is its integral   by improved corrosion resistance, mechanical strength,
            powder bed. This not only provides the material base but also   stiffness, and biocompatibility, these materials have since
            serves as an intrinsic support structure. This dual functionality   become staples in the orthopedic implant domain .
                                                                                                           [53]
            facilitates the creation of complex designs, eliminating the   Furthermore, their versatility is evident in their
            need for supplementary, and sometimes cumbersome,   compatibility with modern AM techniques. Both can be
            support structures. Such an attribute endows PBF with a   processed as powder or wire feedstock, aligning well with
            design adaptability that often surpasses that of DED .  PBF and DED methodologies .
                                                   [51]
                                                                                      [54]
            4. The comprehensive journey of AM-based             While these materials have revolutionized orthopedic
            bone plate production                              treatments, the biomechanics of bone healing introduces
                                                               new challenges. Mechanical stimulation and microinter
            4.1. Selecting materials for orthopedic implants   fragmentary motion play pivotal roles in optimal bone
            Orthopedic implants play a crucial role in addressing bone   regeneration. However, materials such as stainless steel
            defects. Over the years, they have undergone significant   and titanium alloy have a stiffness considerably surpassing

            Table 1. Comparative analysis of key parameters for DED and PBF
            Techniques General process           Subcategory  Feedstock  Thermal   Typical layer   Deposition   References
                                                             form    energy type thickness (µm) rate (kg/h)
            DED      Metal powder or wire is consistently   Laser additive   Powders  Laser  200 – 500  <0.50  [107,108]
                     introduced into the nozzle and subjected   manufacturing
                     to a heat source (laser, electric arc or   DED
                     electron beam). This results in the material
                     being melted to create a molten pool,   Wire and   Wires  Electric arc  1000 – 2000  1.0 – 4.00  [107,109]
                     which conforms to the designated layer   arc additive
                     configuration, and subsequently solidifies   manufacturing
                     onto the substrate. This iterative process   Wire and   Wires  Laser  >1000  0.10 – 2.88  [107,109-111]
                     is reiterated to generate successive molten  laser additive
                     pools layer upon layer until the printing   manufacturing
                     procedure reaches its culmination
                                                 Wire and electron  Wires  Electron   <3000  <19.80  [107,112]
                                                 beam additive       beam
                                                 manufacturing
            PBF      A roller uniformly applies metallic powder  Selective laser   Powders  Laser  25 – 75  0.10 – 0.30 [37,43,47,93,113]
                     onto a substrate, followed by controlled   melting
                     melting using a laser or electron beam.   Selective laser   Powders  Laser  80 – 500  0.10 – 0.20  [79,114]
                     Subsequent layers are added using the roller,   sintering
                     leading to the gradual fabrication of the
                     product. This iterative process continues   Electron beam   Powders  Electron   50 – 100  0.10 – 0.20  [7,35]
                     until the final desired structure is achieved   melting  beam
                     with integrity
            DED: Directed energy deposition, PBF: Powder bed fusion


            Volume 2 Issue 4 (2023)                         5                       https://doi.org/10.36922/msam.2113
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