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Materials Science in Additive Manufacturing                      MAM for orthopedic bone plates: An overview



            designs display mechanical prowess, their biocompatibility   requirements  tailored to  individual patients or specific
            remains a question, underscoring the need for a holistic   fracture types. As a result, this traditional approach struggles
            evaluation.                                        to truly realize patient-specific solutions, underscoring the
              The emergence of patient-specific bone plates through   need for innovative manufacturing strategies.
            AM, driven by 3D imaging-based models from technologies   In the dynamic landscape of orthopedic manufacturing,
            such  as  computed  tomography,  magnetic  resonance   AM  techniques,  especially  PBF,  have  emerged  as  a
                                 [79]
            imaging, and 3D scanners , has marked a transformative   transformative force. They offer both design flexibility
            era. Such plates promise greater precision in screw   and the potential for tailored solutions. For instance, Kim
                                                                   [47]
            placements,  decreased  surgical  durations,  and  enhanced   et al.  leveraged a metal laser melting system to craft a
            patient outcomes. For instance, studies like those from   unique fixation plate tailored for distal radial fractures. In
            Steffen et al.  and Dobbe et al.  testify to the mechanical   biomechanical assessments, these AM plates outperformed
                     [38]
                                     [36]
            robustness and superior pain alleviation associated with   conventional volar locking plates, showcasing their
            these plates. Despite these benefits, challenges persist.   potential to better match individual anatomical
            Advanced imaging, while improving accuracy, can inflate   requirements and reduce stress shielding. A comparative
                                                                               [84]
                               [79]
            time and financial costs . The manufacturing timeline, as   study by Xie  et al.  revealed the biomechanical edge
            highlighted by Teo et al. , could introduce surgical delays.   of plates produced through direct metal laser sintering
                               [37]
            Moreover, a conspicuous gap in the literature pertains to   (DMLS) over CNC-manufactured plates. Although there
            the long-term efficacy and biocompatibility of these plates.  was a slight compromise in fatigue performance, DMLS
                                                               plates comfortably met clinical standards.
              Transitioning  from  the  fully  patient-specific
                                                                                                       [85]
            realm, semi-patient-specific bone plate designs offer   From an economic perspective, Ballard  et al.  shed
            a  harmonious  blend of  mechanical  optimization  and   light  on  the  potential  cost-efficiencies  of  AM  models.
            time and cost efficiency. This approach, which involves   Their findings underscored the benefits of reduced
            tweaking features of a foundational design, synergizes   surgical time and fewer revision surgeries, translating to
            well with AM. Jabran et al.  exemplify this by optimizing   substantial savings for healthcare institutions and patients.
                                 [80]
                                                                            [37]
            features like screw distribution. Yet, many studies in this   Yet, as Teo et al.  pointed out, the real-world feasibility
            domain, such as those by Yan et al. , often eschew clinical   of these AM techniques often hinges on the availability of
                                       [81]
            validation for mechanical assessments. The introduction   both  sophisticated  infrastructure  and  skilled  personnel.
                                                                                                           [34]
            of mechanobiological elements, highlighted by works   In a bid to innovate further, Vijayavenkataraman et al.
            like Subasi et al. , brings added intricacy. While AM has   unveiled an orthopedic bone plate incorporating auxetic
                         [77]
            undoubtedly expanded the horizons of bone plate design,   structures.  This  design  innovation  not  only  curtails  the
            realizing its full potential mandates a more integrated   stress-shielding effect but also offers the flexibility of
            research  approach.  Holistic  studies  that  amalgamate   intraoperative bending.
            mechanical, clinical, and biocompatibility aspects are the   The realm of bone plate manufacturing is witnessing
            need of the hour.                                  transformative changes, particularly with the melding
                                                               of additive and subtractive manufacturing techniques.
            4.3. Technological innovations in bone plate       AM brings to the table its prowess in crafting intricate
            fabrication
                                                               geometries, although often with subpar surface finishes.
            Commercially available bone plates predominantly utilize   This necessitates post-manufacturing processes to
            subtractive manufacturing techniques. This method   enhance surface quality, such as drilling and surface
            encompasses various stages, beginning with raw material   modifications [86,87] . On the other hand, subtractive methods
            formation, and culminating in finishing tasks such as   like CNC machining excel in achieving superior surface
            hole drilling and surface polishing [82,83] . The integration   finishes but grapple  with the complexities of detailed
            of  computer  numerical control (CNC)  technology  into   structures.
            the machining phase offers notable advantages, including   To harness the strengths of both worlds, the fusion of AM
            accelerated production, minimized tolerances, and   and subtractive manufacturing has gained traction . For
                                                                                                        [88]
            enhanced repeatability – qualities that align well with mass   instance, Da Cruz Gomes et al.  employed AM-assisted
                                                                                        [48]
            production objectives.
                                                               investment casting to fabricate NiTi shape memory
              However,  the  rigidity  of  subtractive  manufacturing   alloy bone plates, unveiling notable enhancements in
            becomes evident when confronted with the need for   mechanical properties and biocompatibility. Another leap
            nuanced alterations in bone plate geometry. Specifically,   in this hybrid domain is the work by Lu et al. , where the
                                                                                                   [89]
            it falls short in addressing the diverse and intricate design   synergy of laser- DED with laser shock peening was shown

            Volume 2 Issue 4 (2023)                         8                       https://doi.org/10.36922/msam.2113
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