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            Figure 6. Hydrogels provide support for the cultivation of cerebral and spinal cord organoids. (A) Schematic illustration of the cerebral organoid culture
            system with a combination of 3D BEM hydrogel culture and the microfluidic device. (B) Bioengineering of the brain organoids by the microfluidic BEM
            system improves radial glial generation and cortical organization. Image used with permission from Cho et al.,  Copyright © 2021, Nature Publishing
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            Group. (C) Schematic diagram of the effect of alginate encapsulation on maturation of spinal cord organoids. (D) Alginate supports neurogenesis in
            spinal cord organoids.  Image used with permission from Chooi et al.,  Copyright © 2023, Wiley.
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            Abbreviations: 3D: Three-dimensional; BEM: Brain extracellular matrix.
            Volume 1 Issue 2 (2025)                         16                                doi: 10.36922/or.8262
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