Page 83 - OR-1-2
P. 83
for minimally invasive delivery of large intact neuronal 2024;210:115344.
networks. Adv Healthc Mater. 2015;4(2):301-312.
doi: 10.1016/j.addr.2024.115344
doi: 10.1002/adhm.201400250
168. Bhalerao A, Sivandzade F, Archie SR, Chowdhury EA,
156. Jurga M, Dainiak MB, Sarnowska A, et al. The performance Noorani B, Cucullo L. In vitro modeling of the neurovascular
of laminin-containing cryogel scaffolds in neural tissue unit: Advances in the field. Fluids Barriers CNS. 2020;17(1):22.
regeneration. Biomaterials. 2011;32(13):3423-3434.
doi: 10.1186/s12987-020-00183-7
doi: 10.1016/j.biomaterials.2011.01.049 169. D’Antoni C, Mautone L, Sanchini C, et al. Unlocking neural
157. Rothenbucher TSP, Gurbuz H, Pereira MP, Heiskanen A, function with 3D in vitro models: A technical review of
Emneus J, Martinez-Serrano A. Next generation human self-assembled, guided, and bioprinted brain organoids and
brain models: Engineered flat brain organoids featuring their applications in the study of neurodevelopmental and
gyrification. Biofabrication. 2021;13(1):011001. neurodegenerative disorders. Int J Mol Sci. 2023;24(13):10762.
doi: 10.1088/1758-5090/abc95e doi: 10.3390/ijms241310762
158. Xu L, Ding H, Wu S, et al. Artificial meshed vessel-induced 170. Depla JA, Mulder LA, de Sá RV, et al. Human brain organoids
dimensional breaking growth of human brain organoids and as models for central nervous system viral infection. Viruses.
multiregional assembloids. ACS Nano. 2024;18(38):26201-26014. 2022;14(3):634.
doi: 10.1021/acsnano.4c07844 doi: 10.3390/v14030634
159. Ren Y, Yang X, Ma Z, et al. Developments and opportunities 171. Fan W, Christian KM, Song H, Ming GL. Applications
for 3D bioprinted organoids. Int J Bioprint. 2021;7(3):364. of brain organoids for infectious diseases. J Mol Biol.
2022;434(3):167243.
doi: 10.18063/ijb.v7i3.364
doi: 10.1016/j.jmb.2021.167243
160. Sukhinich K, Shakirova K, Dashinimaev E, Aleksandrova M.
Development of 3D cerebral aggregates in the brain ventricles 172. Sato Y, Asahi T, Kataoka K. Integrative single-cell RNA-
of adult mice. Russ J Dev Biol. 2021;52(3):164-175. seq analysis of vascularized cerebral organoids. BMC Biol.
2023;21(1):245.
doi: 10.1134/S1062360421030061
doi: 10.1186/s12915-023-01711-1
161. Daviaud N, Friedel RH, Zou H. Vascularization and
engraftment of transplanted human cerebral organoids in 173. Chai YC, To SK, Simorgh S, et al. Spatially self‐organized
mouse cortex. eNeuro. 2018;5(6). three‐dimensional neural concentroid as a novel reductionist
humanized model to study neurovascular development. Adv
doi: 10.1523/ENEURO.0219-18.2018 Sci. 2024;11(5):2304421.
162. Mansour AA, Gonçalves JT, Bloyd CW, et al. An in vivo model doi: 10.1002/advs.202304421
of functional and vascularized human brain organoids. Nat
Biotechnol. 2018;36(5):432-441. 174. Kumarasamy M, Sosnik A. Heterocellular spheroids of
the neurovascular blood-brain barrier as a platform for
doi: 10.1038/nbt.4127 personalized nanoneuromedicine. Iscience. 2021;24(3):102183.
163. Revah O, Gore F, Kelley KW, et al. Maturation and circuit doi: 10.1016/j.isci.2021.102183
integration of transplanted human cortical organoids.
Nature. 2022;610(7931):319-326. 175. Abijo AZ, Olatunji SY, Adelodun ST, Asamu MO,
Omeiza NA. Modeling Alzheimer’s disease using cerebral
doi: 10.1038/s41586-022-05277-w organoids: Current challenges and prospects. Brain Organoid
164. Chiaradia I, Lancaster MA. Brain organoids for the study of Syst Neurosci J. 2024;2:53-63.
human neurobiology at the interface of in vitro and in vivo. doi: 10.1016/j.bosn.2024.09.001
Nat Neurosci. 2020;23(12):1496-1508.
176. Kumarasamy M, Sosnik A. Multicellular organoids of the
doi: 10.1038/s41593-020-00730-3 neurovascular blood-brain barrier: A new platform for
165. Pasca SP, Arlotta P, Bateup HS, et al. A framework for neural precision neuronanomedicine. bioRxiv. 2020:249326.
organoids, assembloids and transplantation studies. Nature. doi: 10.1101/2020.08.14.249326
2025;639(8054):315-320.
177. Urrestizala-Arenaza N, Cerchio S, Cavaliere F, Magliaro C.
doi: 10.1038/s41586-024-08487-6 Limitations of human brain organoids to study
166. Alameri A. Microfluidic-based Organoid Vascularization in neurodegenerative diseases: A manual to survive. Front Cell
PDMS Devices Replicated from 3D Printed Molds. Canada: Neurosci. 2024;18:1419526.
McGill University; 2022. doi: 10.3389/fncel.2024.1419526
167. Xu C, Alameri A, Leong W, et al. Multiscale engineering of 178. Balikov DA, Neal EH, Lippmann ES. Organotypic
brain organoids for disease modeling. Adv Drug Deliv Rev. neurovascular models: Past results and future directions.
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