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Tumor Discovery MPTT post-chemotherapy

tumor volume. 3,11,20,21 In one case, it has been used with Consent for publication
curative intent. For MPTTs with distant metastasis,
21
palliative chemotherapy with administration of cisplatin, Written informed consent was obtained from the patient
adriamycin, and vindesine or 5-fluorouracil, followed for publication of this case report and accompanying
by palliative radiotherapy, is recommended by some images.
authors. 3,8,9,11,14,16 However, standardized recommendations Availability of data
are currently lacking due to the scarcity of literature and
the absence of randomized trials. Data can be obtained from the corresponding author upon
reasonable request.
4. Conclusion

The MPTT is now widely recognized in the literature, References
yet it still eludes a definitive nosological diagnostic and, 1. Agarwal C, Pujani M, Raychaudhuri S, Arora S, Rana D,
therefore, a therapeutic consensus. Indeed, the literature Chauhan V. Squamous cell carcinoma versus malignant
expresses a certain ambiguity, and no epidemiological or proliferating trichilemmal tumor: A histopathological
physiological data are 100% certain, for several reasons: dilemma with review of literature. Indian J Dermatol.
the scarcity of reported cases and literature reviews, 2019;64(4):339.
the absence of large case series, the existence of various doi: 10.4103/ijd.IJD_229_17
terminologies, and the clinical and histological similarities 2. Alici O, Keleş MK, Kurt A. A rare cutaneous adnexal tumor:
between MPTT and other tumors, especially squamous Malignant proliferating trichilemmal tumor. Case Rep Med.
cell carcinoma. Regarding the physio-pathological link 2015;2015:742920.
between chemotherapy and the transformation of PTT doi: 10.1155/2015/742920
into MPTT, our case marks only the third reported
instance in the literature. However, these reports are 3. Singh P, Usman A, Motta L, Khan I. Malignant
limited to case studies, offering no conclusive explanations proliferating trichilemmal tumour. BMJ Case
for the potential link between the two. Further specialized Rep. 2018;2018:bcr2018224460.
research and publications are warranted to establish such doi: 10.1136/bcr-2018-224460
a link.
4. Chaichamnan K, Satayasoontorn K, Puttanupaab S,
Acknowledgments Attainsee A. Malignant proliferating trichilemmal
tumors with CD34 expression. J Med Assoc Thai.
None. 2010;93(Suppl 6):S28-S34.
Funding 5. Goyal S, Jain BB, Jana S, Bhattacharya SK. Malignant
proliferating trichilemmal tumor. Indian J Dermatol.
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Conflict of interest doi: 10.4103/0019-5154.92679
6. Headington JT. Tumors of the hair follicle. A review. Am J
The authors declare no conflict of interest. Pathol. 1976;85(2):479-514.
Author contributions 7. Saida T, Oohara K, Hori Y, Tsuchiya S. Development
of a malignant proliferating trichilemmal cyst in a
Conceptualization: Bahaa Razem patient with multiple trichilemmal cysts. Dermatologica.
Investigation: Bahaa Razem, Sami El Hamid, Abdelhakim 1983;166(4):203-208.
Oukerroum
Writing – original draft: Bahaa Razem, Sami El Hamid doi: 10.1159/000249868
Writing – review & editing: Ouail Ilhami, Sami El Hamid, 8. Jagwani A, Palaniandy K, Azizi M. Large malignant
Faiçal Slimani proliferating trichilemmal tumor of the scalp. Surg Chron.
2017;22:236-238.
Ethics approval and consent to participate 9. Bajaj A. The follicular propagation- Malignant proliferating
Our study is exempted from ethical approval. Written trichilemmal tumour. J BioMed Res Innov. 2020;1(1):104.
informed consent was obtained from the patient for 10. Lakhani R, Khullar G, Sharma S. An unusual case of
publication of this case report and accompanying images. co-localization of proliferating trichilemmal tumor and
A copy of the written consent is available for review by the Seborrheic Keratosis. Indian J Dermatol Venereol Leprol.
Editor-in-Chief of this journal on request. 2021;87(4):551-554.

Volume 3 Issue 2 (2024) 4 doi: 10.36922/td.2344