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Tumor Discovery





                                        CASE REPORT
                                        Pyogenic granuloma of maxillary median

                                        gingiva in a pediatric patient: A case report and
                                        literature review



                                                                       2
                                        Takeshi Karube 1  , Terumi Takeuchi , Tatsuya Sakaguchi , Koki Furuya ,
                                                                                                     1
                                                                                         1
                                                 3
                                        Kaori Yago , Hajime Okita , Taneaki Nakagawa , and Seiji Asoda *
                                                              4
                                                                                                1
                                                                                 1
                                        1 Department of Dentistry and Oral Surgery, Keio University School of Medicine, Tokyo, Japan
                                        2 Department of Dentistry, National Cancer Center Hospital East, Chiba, Japan
                                        3 Department of Dentistry and Oral Surgery, International University of Health and Welfare, Mita
                                        Hospital, Tokyo, Japan
                                        4 Division of Diagnostic Pathology, Keio University School of Medicine, Tokyo, Japan

                                        Abstract
                                        Pyogenic granuloma (PG) is a painless pedunculated granulomatous lesion that
                                        develops on the skin and mucous membranes. PG in children is relatively rare. We
                                        herein report a case of PG of the maxillary median gingiva in a pediatric patient. The
                                        patient was a 6-year-old Japanese boy who presented with a painless mass with
                                        bleeding after exfoliation of the left upper deciduous central incisor. The lesion had
                                        undergone continuous, rapid growth for approximately 10 days. Intraoral findings
                                        revealed a painless, elastic, soft, and non-pedunculated mass, measuring 15 × 10 mm,
                                        in the left upper deciduous central incisor area. To differentiate it from malignancy,
            *Corresponding author:      an excisional biopsy was performed on the patient under general anesthesia.
            Seiji Asoda                 Histological findings confirmed that the patient suffered from PG. At the time of
            (asoda@keio.jp)             writing this paper, the patient had been clinically followed up for the 18  month after
                                                                                                  th
            Citation: Karube T, Takeuchi T,   the surgery, showing no signs of tumor recurrence.
            Sakaguchi T, et al. 2024. Pyogenic
            granuloma of maxillary median
            gingiva in a pediatric patient: A case   Keywords: Pyogenic granuloma; Child; Gingiva
            report and literature review. Tumor
            Discov. 2024;3(2):2213.
            doi: 10.36922/td.2213
            Received: November 9, 2023  1. Background
            Accepted: January 16, 2024
                                        Pyogenic granuloma (PG) is a painless pedunculated granulomatous lesion that develops
            Published Online: May 21, 2024  on the skin and mucous membranes. PG of the oral cavity commonly occurs in the lips,
                                                                                             1
            Copyright: © 2024 Author(s).   gingiva, and tongue, but its occurrence in children is relatively rare.  The etiology of PG
            This is an Open-Access article   has not yet been clearly explained in the literature. Differentiating PG from malignant
            distributed under the terms of the   tumors is necessary as they share a similar trait – rapid mass growth.
            Creative Commons Attribution
            License, permitting distribution,   We herein report a case of PG of the maxillary median gingiva in a pediatric patient.
            and reproduction in any medium,
            provided the original work is
            properly cited.             2. Case presentation
            Publisher’s Note: AccScience   The patient was a 6-year-old Japanese boy who presented with a painless mass
            Publishing remains neutral with   with bleeding after exfoliation of the left upper deciduous central incisor. The
            regard to jurisdictional claims in
            published maps and institutional   patient received anti-inflammatory treatment at a nearby dental clinic. Since the
            affiliations.               lesion exhibited continuous, rapid growth for approximately 10  days, the patient


            Volume 3 Issue 2 (2024)                         1                                 doi: 10.36922/td.2213
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