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Tumor Discovery
CASE REPORT
Pyogenic granuloma of maxillary median
gingiva in a pediatric patient: A case report and
literature review
2
Takeshi Karube 1 , Terumi Takeuchi , Tatsuya Sakaguchi , Koki Furuya ,
1
1
3
Kaori Yago , Hajime Okita , Taneaki Nakagawa , and Seiji Asoda *
4
1
1
1 Department of Dentistry and Oral Surgery, Keio University School of Medicine, Tokyo, Japan
2 Department of Dentistry, National Cancer Center Hospital East, Chiba, Japan
3 Department of Dentistry and Oral Surgery, International University of Health and Welfare, Mita
Hospital, Tokyo, Japan
4 Division of Diagnostic Pathology, Keio University School of Medicine, Tokyo, Japan
Abstract
Pyogenic granuloma (PG) is a painless pedunculated granulomatous lesion that
develops on the skin and mucous membranes. PG in children is relatively rare. We
herein report a case of PG of the maxillary median gingiva in a pediatric patient. The
patient was a 6-year-old Japanese boy who presented with a painless mass with
bleeding after exfoliation of the left upper deciduous central incisor. The lesion had
undergone continuous, rapid growth for approximately 10 days. Intraoral findings
revealed a painless, elastic, soft, and non-pedunculated mass, measuring 15 × 10 mm,
in the left upper deciduous central incisor area. To differentiate it from malignancy,
*Corresponding author: an excisional biopsy was performed on the patient under general anesthesia.
Seiji Asoda Histological findings confirmed that the patient suffered from PG. At the time of
(asoda@keio.jp) writing this paper, the patient had been clinically followed up for the 18 month after
th
Citation: Karube T, Takeuchi T, the surgery, showing no signs of tumor recurrence.
Sakaguchi T, et al. 2024. Pyogenic
granuloma of maxillary median
gingiva in a pediatric patient: A case Keywords: Pyogenic granuloma; Child; Gingiva
report and literature review. Tumor
Discov. 2024;3(2):2213.
doi: 10.36922/td.2213
Received: November 9, 2023 1. Background
Accepted: January 16, 2024
Pyogenic granuloma (PG) is a painless pedunculated granulomatous lesion that develops
Published Online: May 21, 2024 on the skin and mucous membranes. PG of the oral cavity commonly occurs in the lips,
1
Copyright: © 2024 Author(s). gingiva, and tongue, but its occurrence in children is relatively rare. The etiology of PG
This is an Open-Access article has not yet been clearly explained in the literature. Differentiating PG from malignant
distributed under the terms of the tumors is necessary as they share a similar trait – rapid mass growth.
Creative Commons Attribution
License, permitting distribution, We herein report a case of PG of the maxillary median gingiva in a pediatric patient.
and reproduction in any medium,
provided the original work is
properly cited. 2. Case presentation
Publisher’s Note: AccScience The patient was a 6-year-old Japanese boy who presented with a painless mass
Publishing remains neutral with with bleeding after exfoliation of the left upper deciduous central incisor. The
regard to jurisdictional claims in
published maps and institutional patient received anti-inflammatory treatment at a nearby dental clinic. Since the
affiliations. lesion exhibited continuous, rapid growth for approximately 10 days, the patient
Volume 3 Issue 2 (2024) 1 doi: 10.36922/td.2213

