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Artificial Intelligence in Health                           Rotational thermography for breast cancer screening



            explored. Results indicate the system’s promise as an   the results and should be considered when interpreting
            effective  diagnostic  tool  for  early  detection  of  high-risk   the findings. One potential source of bias arises from the
            individuals. The system’s non-invasive and non-contact   sample population, which may not fully represent the
            nature makes it well-suited for population screening,   general population due to demographic variations and
            despite challenges with ambient temperature adjustments.  differences in breast cancer prevalence, thereby potentially

              After considering the experts’ concerns, we conducted   limiting the study’s generalizability.
            a thorough comparative analysis, including using the   Confounding variables such as variations in breast
            system with biopsy and USG. This analysis was carried out   density, tissue composition, and patient positioning during
            with great attention to detail. This analysis addresses the   imaging could have affected the accuracy and consistency
            expert’s and concerned doctors’ request for a comparison   of the system. Although the study attempted to control
            with established diagnostic methods. The system exhibited   for these factors, they may have introduced some degree
            a sensitivity comparable to that of biopsy (90.2% vs. 88.6%)   of variability in the results. External factors such as
            and USG (90.2% vs. 89.7%). Furthermore, the system   equipment quality and maintenance, technician expertise,
            displayed competitive specificity, with respective values of   and interpretation differences among medical professionals
            82.8%, 84.6%, and 82.4% for biopsy, USG, and the system.   may have also impacted the study’s outcomes. Moreover,
            This comprehensive analysis not only addresses reviewers’   relying on USG and biopsy reports to cross-validate the
            concerns but also underscores the potential utility of the   system’s performance introduces potential dependencies
            system as a valuable diagnostic tool.              on the accuracy and reliability of these other diagnostic
                                                               modalities.
            5. Conclusion
                                                                 The study progressed iteratively, with each phase’s
            IR imaging plays a crucial role in various medical   findings and feedback shaping the design and objectives
            applications,  emphasizing  IR  image  acquisition  of the subsequent phase. This approach allowed us to
            techniques. This paper reported different types of IR image   refine methods and address challenges progressively. By
            acquisition systems based on trials in a hospital setup   enhancing techniques and analyses based on results-
            and conclusively identified the superior one. Key features   driven objectives, each phase naturally evolved, focusing
            of the proposed imaging system include a touchless and   on enhancing the efficiency and accuracy of our breast
            painless IR camera-based system for maximum patient   cancer screening imaging system. In terms of sample size,
            comfort;  gantry  rotation  for  acquiring  multiple  breast   we acknowledge that the varying sizes across phases may
            angles; dynamic IR image collection within a temperature-  impact the overall consistency of the results. However,
            controlled chamber; and a simplified user interface for   the number of subjects available for each phase depended
            data collection by technicians, IR image analysis experts,   on live patient availability during the study period at the
            and doctors.                                       hospital. Practical constraints such as time and resource
              The primary challenge in this study was managing   limitations influenced sample sizes, despite efforts to
            patients  with  varied  health  conditions.  During  the  early   maintain consistency. While we tried to work with
            stages of  development,  patients  had to wait a long  time   consistent  sample  sizes,  external  factors  such  as  patient
            to reach a stable room temperature. However, as the   availability and medical considerations posed challenges.
            development of the novel data acquisition technique   However,  our  phased  approach  enabled  us  to  optimize
            progressed, the evolved system became more user-friendly   methods  and techniques,  yielding  improved  results  in
            and efficient regarding imaging quality. The next challenge   each subsequent phase. Our study focused on real-world
            addressed was maintaining a constant ambient temperature   application and practical implementation, requiring
            during data collection, which was the most difficult task. It   flexibility in our approach.
            was overcome by implementing a temperature-controllable   In addition, the challenges faced during data collection,
            enclosure. Here, two ambient temperatures have been   such as maintaining a constant ambient temperature and
            taken. The higher temperature was 25°C, and the lower   managing patients with diverse health conditions, affected
            temperature was 23°C. The mean temperature adjustment   the precision and consistency of the imaging process.
            for each subject is 1°C.                           While we addressed these challenges throughout the study,
              Finally, IR image analysis software was developed,   residual variability may have affected the results. Overall,
            incorporating machine learning algorithms that produced   while the study presents promising findings, we carefully
            excellent results. These findings were cross-validated using   considered its limitations and potential sources of bias
            USG and biopsy reports. However, several limitations   when evaluating the system’s effectiveness and applicability
            were identified during this study that may have influenced   in broader clinical settings. Future research should address


            Volume 1 Issue 3 (2024)                         76                               doi: 10.36922/aih.3312
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