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Artificial Intelligence in Health                                       ViT for neurodegeneration diagnosis



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            Pharmaceutical Company; and Transition Therapeutics.   Dementia go Undiagnosed Across the Globe - World Alzheimer
            The Canadian Institutes of Health Research provided   Report Reveals. Available from: https://www.alzint.org/
            funds to support ADNI clinical sites in Canada. Private   news/events/news/over/41/million/cases/of/dementia/go/
            sector contributions are facilitated by the Foundation   undiagnosed-across-the-globe-world-alzheimer-report-
            for the National Institutes of Health (https://www.fnih.  reveals [Last accessed on 2025 Mar 30].
            org/). The grantee organization is the Northern California   4.   Etminani K, Soliman A, Davidsson A,  et al. A  3D deep
            Institute for Research and Education, and the study was   learning model to predict the diagnosis of dementia with
            coordinated by the Alzheimer’s Therapeutic Research   lewy bodies, Alzheimer’s disease, and mild cognitive
            Institute at the University of Southern California. ADNI   impairment using brain 18F-FDG PET. Eur J Nucl Med Mol
            data were disseminated by the Laboratory for Neuro    Imaging. 2022;49(2):563-584.
            Imaging at the University of Southern California. Farzaneh       doi: 10.1007/s00259-021-05483-0
            Etminani and Amira Soliman are supported by Center for   5.   Ding Y, Sohn JH, Kawczynski MG, et al. A deep learning
            Applied Intelligent Systems Research in Health (CAISR   model to predict a diagnosis of alzheimer disease by using
            Health) funded by Knowledge Foundation (grant no.:    18 F-FDG PET of the brain. Radiology. 2019;290(2):456-464.
            20200208 01H).
                                                                   doi: 10.1148/radiol.2018180958
            Conflict of interest                               6.   Dosovitskiy A, Beyer L, Kolesnikov A,  et  al.  An  Image is
            The authors declare no conflicts of interest.         Worth 16x16 Words: Transformers for Image Recognition at
                                                                  Scale. [ArXiv Preprint]; 2020.
            Author contributions                               7.   The Alzheimer’s Disease Neuroimaging Initiative. Alzheimer’s
                                                                  Disease Neuroimaging Initiative (ADNI).  Available  from:
            Conceptualization: All authors                        https://adni.loni.usc.edu [Last accessed on 2025 Mar 30].
            Formal analysis: Pooriya Khorramyar, Amira Soliman
            Investigation: All authors                         8.   Vaswani A, Shazeer N, Parmar N, et al. Attention is all you
            Methodology: Pooriya Khorramyar, Amira Soliman        need. Advances in Neural Information Processing Systems.
                                                                  2017. p. 30.
            Writing–original draft: Pooriya Khorramyar
            Writing–review & editing: All authors              9.   Nobili F, Arbizu J, Bouwman F, et al. European association
                                                                  of nuclear medicine and European academy of neurology
            Ethics approval and consent to participate            recommendations for the use of brain  F-fluorodeoxyglucose
                                                                                             18
                                                                  positron emission  tomography in neurodegenerative
            Please visit the ADNI documentation at https://adni.loni.  cognitive impairment and dementia: Delphi consensus. Eur
            usc.edu/help-faqs/adni-documentation/.                J Neurol. 2018;25(10):1201-1217.

            Consent for publication                                doi: 10.1111/ene.13728
            Please visit the ADNI documentation at https://adni.loni.  10.  Mayo  Foundation  for Medical Education  and  Research
                                                                  (MFMER).  Positron  Emission  Tomography  Scan. Available
            usc.edu/help-faqs/adni-documentation/.
                                                                  from:   https://www.mayoclinic.org/tests/procedures/pet/
            Availability of data                                  scan/about/pac-20385078 [Last accessed on 2025 Mar 30].
                                                               11.  Cleveland Clinic.  PET Scan. Available from: https://
            To download the dataset, please visit the ADNI’s web   my.clevelandclinic.org/health/diagnostics/10123-pet-scan
            page  at https://adni.loni.usc.edu/. The  code  is available   [Last accessed on 2025 Mar 30].
            on the project’s GitHub repository (https://github.com/
            Pooriya-Kh/NDD_ViT).                               12.  Rolls ET, Huang CC, Lin CP, Feng J, Joliot M. Automated
                                                                  anatomical labelling atlas 3. Neuroimage. 2020;206:116189.
            References                                             doi: 10.1016/j.neuroimage.2019.116189
            1.   World Health Organization (WHO).  Dementia  Key  Facts.   13.  Mayo  Foundation  for Medical Education  and  Research
               Available  from:  https://www.who.int/news-room/fact-  (MFMER).  Mild Cognitive Impairment (MCI).  Available


            Volume 2 Issue 4 (2025)                         44                          doi: 10.36922/AIH025140026
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