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Advanced Neurology Futile recanalization of acute basilar artery occlusion

Table 1. Demographic characteristics and clinical data of the ABAO patients treated with EVT
Variables FR (n=72) Non-FR (n=38) P-value
Age (mean±SD year) 64.71±10.77 60.76±14.07 0.104
Male (n [%]) 48 (66.7%) 30 (78.9%) 0.177
Hypertension (n [%]) 45 (62.5%) 21 (55.3%) 0.461
Diabetes mellitus (n [%]) 23 (31.9%) 11 (28.9%) 0.746
Coronary heart disease (n [%]) 14 (19.4%) 5 (13.2%) 0.407
Atrial fibrillation (n [%]) 24 (33.3%) 10 (26.3%) 0.449
Prior stroke (n [%]) 28 (38.9%) 12 (31.6%) 0.449
Systolic pressure (mean±SD mm Hg) 147.18±27.71 142.84±25.15 0.426
Diastolic pressure (mean±SD mm Hg) 83.89±14.69 86.54±13.21 0.358
SII (median, IQR) 1589.82 (794.72 – 2515.65) 771.30 (399.17 – 1518.11) 0.001
Ln (SII) (mean±SD) 7.27±0.89 6.65±0.82 <0.001
SIRI (median [IQR]) 3.02 (1.54 – 6.05) 1.45 (0.77 – 3.43) 0.001
Ln (SIRI) (mean±SD) 1.09±0.89 0.47±0.87 0.001
RPR 0.06 (0.05 – 0.08) 0.07 (0.06 – 0.08) 0.211
ALP (U/L) 84.64±25.43 72.32±18.62 0.01
ChE (U/L) 7740.46±1791.61 7396.11±1703.88 0.332
TOAST 0.048
LAA (n [%]) 44 (61.1%) 19 (50%)
CE (n [%]) 20 (27.8%) 7 (18.4%)
SAA (n [%]) 2 (2.8%) 7 (18.4%)
SOE (n [%]) 3 (4.2%) 3 (7.9%)
SUE (n [%]) 3 (4.2%) 2 (5.3%)
Intravenous rt-PA (n [%]) 25 (34.7%) 5 (13.2%) 0.016
NIHSS score (median, IQR) 29 (19 – 35) 19 (10 – 35) 0.013
OPT (mean±SD min) 365.04±184.75 445.43±172.01 0.219
ORT ( mean±SD min) 445.43±172.01 384.05±156.42 0.069
Procedure time (min) 102.85±42.12 75.82±27.84 0.001
Occlusion site 0.971
Proximal BA (n [%]) 27 (37.5%) 16 (42.1%)
Middle BA (n [%]) 16 (22.2%) 8 (21.1%)
Distal BA (n [%]) 13 (18.1%) 6 (15.8%)
Tandem lesions (n [%]) 16 (22.2%) 8 (21.1%)
ACGS-BAO (median [IQR]) 2 (2 – 3) 3 (2 – 4) <0.001
pc-ASPECTS on NCCT (median [IQR]) 8 (7 – 10) 9 (8 – 10) 0.083
Infusion of tirofiban (n [%]) 30 (41.7%) 19 (50%) 0.403
Surgical modalities 0.003
Aspiration thrombectomy (n [%]) 15 (20.8%) 11 (28.9%)
Stent-retriever thrombectomy (n [%]) 41 (56.9%) 9 (23.7%)
Intra-arterial thrombolysis (n [%]) 16 (22.2%) 18 (47.4%)
Malignant cerebral edema (n [%]) 17 (23.6%) 0 (0%) 0.001
HT (n [%]) 23 (31.9%) 2 (5.3%) 0.001
Abbreviations: ABAO: Acute basilar artery occlusion; ACGS-BAO: Angiographic Collateral Grading System for Basilar Artery Occlusion; ALP: Alkaline
phosphatase; BA: Basilar artery; CE: Cardioembolism; ChE: Cholinesterase; EVT: Endovascular treatment; FR: Futile recanalization; HT: Hemorrhagic
transformation; IQR: Interquartile range; LAA: Large-artery atherosclerosis; Ln (SII): Natural logarithm-transformed of systemic immune inflammation
index; Ln (SIRI): Natural logarithm-transformed of systemic inflammation response index; NCCT: Non-contrast computed tomography; NIHSS: National
Institutes of Health Stroke Scale; OPT: Onset-to-groin puncture time; ORT: Onset-to-recanalization time; pc-ASPECTS: Posterior Circulation Acute Stroke
Prognosis Early Computed Tomography Score; RPR: Red blood cell distribution width-platelet ratio; rt-PA: Recombinant tissue plasminogen activator;
SAA: Small-artery occlusion lacunar; SD: Standard deviation; SII: Systemic immune inflammation index; SIRI: Systemic inflammation response index;
SOE: Stroke of other determined etiology; SUE: Stroke of undetermined etiology; TOAST: Trial of Org 10172 in Acute Stroke Treatment.

Volume 2 Issue 4 (2023) 5 https://doi.org/10.36922/an.1641