Page 29 - AN-2-4
P. 29

Advanced Neurology                                          Futile recanalization of acute basilar artery occlusion



            analytical framework may compromise a comprehensive   Ethics approval and consent to participate
            assessment of the inflammation status among the study
            participants. Finally, it is essential to underscore that all   This study was approved by the Medical Ethics Committee
            procedures within the purview of this study were executed   of the Affiliated Hospital of Xuzhou Medical University
            by multiple neuro-intervention specialists. The variability   (approval number: XYFY2018-KL078). Written informed
            in operators’ experience levels and distinct operational   consent was individually obtained from all patients. We
            methodologies potentially introduces an element of   affirm that all methods conducted in our study adhered to
                                                               the pertinent guidelines and regulations.
            subjectivity that may impact vessel recanalization.
            5. Conclusion                                      Consent for publication
                                                               Not applicable.
            In  conclusion,  ACGS-BAO  and  pre-procedural  SIRI
            stand as standard, readily available metrics in clinical   Availability of data
            practice. They respectively evaluate the condition
            of basilar collateral circulation and the extent of the   The datasets used and analyzed during the current study are
            inflammatory response, both intrinsically linked to the   available from the corresponding author upon reasonable
            occurrence of FR post-EVT. Our study affirms a negative   request.
            correlation between collateral circulation status and FR   References
            while conversely establishing a positive correlation with
            inflammation levels. The combined use of these two   1.   Israeli-korn SD, Schwammenthal Y, Yonash-Kimchi T, et al.,
            biomarkers proves more predictive of post-operative   2010, Ischemic stroke due to acute basilar artery occlusion:
            FR than the isolated use of either marker. This finding   proportion and outcomes. Isr Med Assoc J, 12: 671–675.
            holds significant implications for tailoring individualized   2.   Mattle  HP, Arnold M, Lindsberg PJ,  et  al., 2011, Basilar
            treatment strategies and mitigating the risk of additional   artery occlusion. Lancet Neurol, 10: 1002–1014.
            injuries.                                          3.   Gory B, Eldesouky I, Sivan-Hoffmann R,  et al., 2016,
            Acknowledgments                                       Outcomes of stent retriever thrombectomy in basilar artery
                                                                  occlusion: An observational study and systematic review.
            None.                                                 J Neurol Neurosurg Psychiatry, 87: 520–525.
                                                                  https://doi.org/10.1136/jnnp-2014-310250
            Funding
                                                               4.   Zi W, Qiu Z, Wu D, et al., 2020, Assessment of endovascular
            The study supported by the National Health Commission   treatment for acute basilar artery occlusion via a nationwide
            Brain Prevention Committee, under the grant “Research   prospective registry. JAMA Neurol, 77: 561–573.
            and Promotion Project of Appropriate Technology       https://doi.org/10.1001/jamaneurol.2020.0156
            Intervention for High-risk Groups of Stroke in China”
            (GN-2018R0009),  and  “Xuzhou  Promoting  Science  and   5.   Jovin TG, Li C, Wu L, et al., 2022, Trial of thrombectomy
            Technology Innovation Project” (KC22241).             6 to 24 hours after stroke due to basilar-artery occlusion.
                                                                  N Engl J Med, 387: 1373–1384.
            Conflict of interest                                  https://doi.org/10.1056/NEJMoa2207576

            The authors declare that they have no competing interests.  6.   Tao C, Nogueira RG, Zhu Y, et al., 2022, Trial of endovascular
                                                                  treatment of acute basilar-artery occlusion. N Engl J Med,
            Author contributions                                  387: 1361–1372.

            Conceptualization: Yao-Wu Liu, Bo Du, De-Qin Geng     https://doi.org/10.1056/NEJMoa2206317
            Data curation: Yao-Wu Liu, Qi-Yang Yuan, Shuo Li, Jin-Jin   7.   Hussein HM, Georgiadis AL, Vazquez G,  et al., 2010,
               Yang                                               Occurrence and predictors of futile recanalization following
            Formal analysis: Yao-Wu Liu, Qi-Yang Yuan, Bo Du      endovascular treatment among patients with acute ischemic
            Investigation: Dian-Shuai Gao, De-Qin Geng            stroke: A  multicenter  study.  AJNR Am J Neuroradiol,
            Methodology: Yao-Wu Liu, Shi-Guang Zhu, De-Qin Geng   31: 454–458.
            Writing – original draft: Yao-Wu Liu, Qi-Yang Yuan, Bo Du     https://doi.org/10.3174/ajnr.A2006
            Writing – review & editing: Yao-Wu Liu, Bilal Muhammad,
               Yan-Bo Cheng, Shi-Guang Zhu, De-Qin Geng        8.   Tomsick T, Broderick J, Carrozella J,  et al., 2008,
                                                                  Revascularization results in the interventional management
              All authors read and approved the final manuscript.  of stroke II trial. AJNR Am J Neuroradiol, 29: 582–587.



            Volume 2 Issue 4 (2023)                         10                        https://doi.org/10.36922/an.1641
   24   25   26   27   28   29   30   31   32   33   34