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Advances in Radiotherapy &

                                                                             Nuclear Medicine



                                        CASE REPORT
                                        A case report of refractory pulmonary

                                        adenocarcinoma



                                        Haiyan Li, Chifeng Xu, and Xia Lu*
                                        Department of Nuclear Medicine, Northern Jiangsu People’s Hospital, Yangzhou, China



                                        Abstract

                                        As one of the most common types of carcinomas, lung cancer has high incidence
                                        and  mortality  rates.  Among  the  pathological  types  of  lung  cancer,  pulmonary
                                        adenocarcinoma is the most prevalent. Advancements in medical treatments have
                                        contributed  to  improved  prognosis  in  pulmonary  adenocarcinomas.  However,
                                        this case report revealed a rare refractory lung adenocarcinoma, suggesting that
                                        further research and robust management strategies are needed to improve clinical
                                        outcomes. In this regard,  F-fluorodeoxyglucose positron emission tomography/
                                                              18
                                        computed tomography plays a very important role in the comprehensive evaluation
                                        of glucose metabolic activity in lung adenocarcinoma and the progression of
                                        metastasis in distant organs.

                                        Keywords: Pulmonary adenocarcinoma;  F-fluorodeoxyglucose positron emission
                                                                        18
                                        tomography/computed tomography; Treatment; Prognosis




            *Corresponding author:      1. Background
            Xia Lu
            (lxgf2222@163.com)          Pathological subtypes and clinical staging of lung adenocarcinoma affect patient
                                        treatment and prognosis directly. Good outcomes come from a systematic, standardized,
            Citation: Li H, Xu C, Lu X, 2023,
            A case report of refractory   and scientific treatment plan based on tumor type and precise clinical staging. This
            pulmonary adenocarcinoma. Adv   case is a rare refractory papillary adenocarcinoma, presented with a small pulmonary
            Radiother Nucl Med.         primary lesion but early extensive metastases and poor outcomes after robust systematic
            https://doi.org/10.36922/arnm.0883
                                        treatment medical treatment.
            Received: April 29, 2023
            Accepted: June 16, 2023     2. Case presentation
            Published Online: June 28, 2023  A 53-year-old man, with pain in the right shoulder joint as well as limited movement
                                        for 2 months and a family history of gastrointestinal malignant tumors, was admitted
            Copyright: © 2023 Author(s).
            This is an Open-Access article   to the hospital for further diagnosis and treatment. The bone scan (Figure 1A) showed
            distributed under the terms of the   increased radioactivity at the proximal end of the right humerus, the left sixth rib, and
            Creative Commons Attribution   the first lumbar vertebra that diagnosed metastatic lesions. Computed tomography
            License, permitting distribution,
            and reproduction in any medium,   (CT) scanning of the right shoulder joint (Figure 1B and C) presented destruction of
            provided the original work is   the right humerus with surrounding soft-tissue masses. CT plain examination of the
            properly cited.             chest (Figure 1E and F) detected a nodule in the lower lobe near the pleura of the left
            Publisher’s Note: AccScience   lung and sized 24 mm × 18 mm, which has small bubbles inside. Pathological findings
            Publishing remains neutral with   validated the metastatic lesions of the humerus (Figure 1D) were poorly differentiated
            regard to jurisdictional claims in
            published maps and institutional   adenocarcinoma of non-small cell lung cancer (NSCLC) from the lower lobe of the
            affiliations.               left  lung  (Figure  1G).  F-fluorodeoxyglucose  positron  emission  tomography/CT
                                                            18

            Volume 1 Issue 1 (2023)                         1                       https://doi.org/10.36922/arnm.0883
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