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Brain & Heart                                                          Pictorial rendition pulmonary stenosis



            vessels.  In 1967, Porstmann et al. described percutaneous   A            B
                 10
            occlusion of patent ductus arteriosus (PDA).  Shortly
                                                  11
            thereafter, Rashkind and Cuaso developed different PDA
            occluding devices.  In 1976, King  et al. introduced a
                           12
            device to close atrial septal defects (ASDs).  Subsequently,
                                              13
            Rashkind and Cuaso designed a different ASD occluding
            device.  In 1964, Dotter and Judkins proposed the concept
                 14
            of stents.  The introduction of the spiral coil-spring device
                   1
            by Dotter  and stainless steel mesh stents by Palmaz et al. 16
                   15
            followed. The author utilized these devices and subsequently
            developed  transcatheter  techniques  during  his  academic
            practice over the last four decades. Prospective data
            collection before the procedure and during follow-up was   Figure  1.  The  procedure  of  balloon  pulmonary  valvuloplasty  involves
            secured with appropriate Food and Drug Administration   the placement of a balloon valvuloplasty catheter through the stenotic
            and local institutional review board approvals as per the   pulmonary valve and inflating it with diluted contrast material. (A)
            requirements of that time. The objective of this paper is to   Balloon waisting is observed as the balloon is inflated (arrows), a result
            present a pictorial rendition of the author’s observations on   of  the  narrowed  pulmonary  valve.  (B)  Disappearance  of  the  waisting
                                                               (arrows) is observed as the balloon is further inflated, leading to the relief
            balloon valvuloplasty/angioplasty procedures, transcatheter   of pulmonary valve obstruction. Only lateral views are shown. Modified
            occlusion practices, and stent implantation techniques. Due   from Rao. 19
            to the voluminous amount of material, the presentation is
            divided into multiple parts. This paper, which constitutes   A            B
            the first part of the series, reviews balloon pulmonary
            valvuloplasty (BPV) of pulmonary stenosis (PS). Subsequent
            papers discuss other balloon valvuloplasty/angioplasty
            procedures, transcatheter occlusion techniques, and stent
            implantations.

            2. Isolated stenosis of the pulmonary valve
            Grüntzig’s technique  was employed by Kan  et al. in
                             2-5
            the early 1980s to dilate stenotic pulmonary valves.
                                                          6
            Eventually, BPV became the procedure of choice to address
            pulmonary valve stenosis.  The indications for BPV are   Figure 2. (A) Balloon waisting in a neonate. (B) The waisting is eliminated
                                 17
            similar to those used for surgical valvotomy, specifically   as the balloon is inflated. The radiograms are recorded in a sitting-up
            pulmonary valve peak systolic pressure gradients higher   view. Descending aorta (DAo), endotracheal tube (ET), and nasogastric
            than 50 mmHg.  In this section, the technique and results   tube (NG) are labeled. Adopted from Rao et al. 20
                        18
            of BPV to treat valvar PS are reviewed.
                                                               (Figure  7). Reviewing angiograms and echocardiograms
            2.1. BPV techniques
                                                               following BPV revealed free excursion of the leaflets
            Examples of BPV techniques are presented in Figures 1-3.  of the pulmonary valve with a reduction of pulmonary
                                                               valve doming. In patients with right atrium-to-left atrium
            2.2. Immediate results                             shunting via an atrial defect before BPV, the atrial shunt
            Rao  evaluated the immediate outcomes of BPV in the   disappeared or reversed (Figure  8) following successful
               19
            mid-1980s. Subsequently, the immediate outcomes of a   BPV. However, some patients developed RV infundibular
            higher number of patients  were investigated, revealing   stenosis, which will be reviewed in the next section.
                                  21
            a reduction in pulmonary valve peak-to-peak systolic   Most patients no longer required surgery, and with the
            pressure  gradients  and  peak  systolic  pressures  in  the   exception of neonates, all patients were discharged on the
            right ventricle (RV) following BPV. There was also a   day following the BPV procedure. 17,19,21  The immediate
            slight increase in pressures in the pulmonary artery   outcomes of BPV documented by other cardiologists 22-42
            (Figures  4  and  5);  however,  the  cardiac  index  remained   during the 5-year period (1982 – 1987) following the
            unchanged.  The narrow jet of contrast across the stenotic   initial  description of  BPV  aligned  with  the  Rao,   Rao,
                     19
                                                                                                       17
                                                                                                            19
            pulmonary valve remarkably increased following BPV   and Rao  et  al.’s  observations. More recent studies of
                                                                            21
            (Figure  6). The dimension of the RV became smaller   BPV performed between 2007 and 2020, published in
            Volume 2 Issue 1 (2024)                         2                         https://doi.org/10.36922/bh.2406
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