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Eurasian Journal of
Medicine and Oncology WGCNA and LASSO for osteoporosis biomarkers
A B C
D E F
G
Figure 7. Validation of hub gene expression in an external GSE35956 dataset. Differential analysis of (A) LOC286177, (B) NUCB1, (C) PEX19, (D) MTA1,
(E) DRAP1, (F) PCDHGA1, and (G) PRPF39 expresison between healthy and OP groups. Group description: N, normal group; T, test group comprising
osteoporosis (OP) patients.
Abbreviations: NUCB1: Nucleobindin 1; PEX19: Peroxisomal biogenesis factor 19; MTA1: Metastasis associated 1; DRAP1: DRA aassociated protein 1;
PCDHGA1: Protocadherin gamma A1; PRPF39: Pre-mRNA processing factor 39.
A B
Figure 8. ROC curve analysis. ROC curve evaluating the diagnostic performance of hub genes in the (A) GSE35958 and (B) GSE35956 datasets.
Abbreviations: AUC: Area under the curve; ROC: Receiver operating characteristic.
Volume 9 Issue 3 (2025) 270 doi: 10.36922/EJMO025240252
