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Engineering Science in
            Additive Manufacturing                                                       Experimental statistics in AM




            Table 3. Overview of key concepts in statistics and experimental design relevant to AM research
            Category               Topic              Description/goal                   Examples
            DOE and ANOVA feature Blocks      Reduce variability by grouping similar   Blocking by machine, operator, day
                                              experimental units
            DOE and ANOVA feature Model adequacy   Ensure model assumptions are met  Residual plots, normality checks, and
                              checks                                       homoscedasticity
            DOE and ANOVA feature Random order  Avoid confounding with time-related effects Randomized run order in DOE
            DOE and ANOVA feature Model selection  Choose the best-fitting and parsimonious   AIC, BIC, stepwise selection
                                              model
            DOE and ANOVA feature Sample size   Ensure sufficient power for detecting effects  Power analysis, economic justification for sample
                              justification                                size
            Statistical analysis  ANOVA       Test differences among group means  One-way ANOVA, two-way ANOVA, repeated
                                                                           measures ANOVA
            Statistical analysis  Confidence intervals  Estimate the range of parameter values  95% CI for mean or regression coefficients
            Statistical analysis  KS-Test     Compare the distribution of data with the   Kolmogorov–Smirnov test for normality, a subset of
                                              reference distribution       goodness of fit tests
            Statistical analysis  Mann–Whitney U test Compare medians of two independent   Example of non-parametric statistics such as the
                                              groups                       Kruskal–Wallis test
            Statistical analysis  t-tests     Compare the means of groups  One-sample, two-sample, and paired t-test
            Statistical analysis  Bayesian statistics  Update beliefs with data  Bayesian inference, priors, and posteriors
            Statistical analysis  Descriptive statistics  Summarize data   Mean, median, variance, and kurtosis
            Statistical analysis  Machine learning  Model complex relationships or   Decision trees, random forests, and neural networks
                                              classifications
            Statistical analysis  Regression  Model the relationship between variables  Linear regression, logistic regression, and
                                                                           polynomial regression
            Experimental design types Box–Behnken  Optimize the response surface with fewer   3-level design excluding extremes
                                              runs
                                                                                      k
            Experimental design types Fractional factorial  Reduce runs using a subset of factorial   Half fraction of 2  design
                                              combinations
            Experimental design types One factor at a time  Vary one factor while holding others   Simple screening method
                                              constant
            Experimental design types Repeated trials  Estimate variability and improve reliability  Performing the same experiment multiple times
            Experimental design types Taguchi  Robust design emphasizing signal-to-noise   Orthogonal arrays for process optimization
                                              ratios
            Experimental design types Central composite  Fit quadratic models in response surface   Axial points+factorial design
                                              methodology
                                                                            k
            Experimental design types Full factorial  Study all combinations of factors  2  full factorial design
            Experimental design types Single factor   Investigate one factor in detail  Compare multiple levels of a single factor
            Experimental design types Randomly distributed  Capture variability across random settings  Random selection of design points
                              factor levels
            Abbreviations: AIC: Akaike information criterion; AM: Additive manufacturing; ANOVA: Analysis of variance; BIC: Bayesian information criterion;
            CI: Confidence interval; DOE: Design of experiments.


            To better understand trends in experimental design over   analysis. Each of these variables is binary. In addition,
            time, we performed a cluster analysis to automatically   we also input the type of experimental design and the
            categorize different papers and then see how frequencies   type of data analysis used. Finally, we incorporated the
            in these groups change over time. The variables that   sample size. While this is a continuous variable, all other
            were used in the cluster analysis were whether a paper   factors are categorical. As we used Gower distance to
            used blocking, randomization, checked for model    calculate the dissimilarity matrix,  which is only valid
                                                                                           30
            adequacy, performed model selection, and used a power   for categorical variables, we converted the sample size


            Volume 1 Issue 4 (2025)                         7                          doi: 10.36922/ESAM025340021
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