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Gene & Protein in Disease                                                   Bioinformatics study of PCNP



            Author contributions                               7.   Rechsteiner M, Rogers S, 1996, PEST sequences and
                                                                  regulation by proteolysis. Trends Biochem Sci, 21(7): 267–271.
            Conceptualization: Nazeer Hussain Khan and Wenkang
               Wang                                               https://doi.org/10.1016/s0968-0004(96)10031-1
            Data curation: Nazeer Hussain Khan and Wenkang Wang  8.   Salazar-Retana AL, Maruri-López I, Hernández-Sánchez IE,
            Formal analysis:  Nazeer Hussain Khan, Wenkang Wang,   et al., 2019, PEST sequences from a cactus dehydrin regulate
               Muhammad Shahid, Saadullah Khatak, and Ebenezeri   its proteolytic degradation. PeerJ, 7: e6810.
               Erasto Ngowi                                       https://doi.org/10.7717/peerj.6810
            Investigation: Muhammad Shahid, Saadullah Khatak, and   9.   Mori T, Li Y, Hata H, et al., 2002, NIRF, a novel RING finger
               Ebenezeri Erasto Ngowi                             protein, is involved in cell-cycle regulation. Biochem Biophys
            Methodology: Muhammad Shahid, Saadullah Khatak, and   Res Commun, 296(3): 530–536.
               Ebenezeri Erasto Ngowi                             https://doi.org/10.1016/s0006-291x(02)00890-2
            Resources: Salma S. Mahmoud, Hao-Jie Chen, Lei Qian,
               Yangzhe Qin, Dong-Dong Wu, Chun Yang Zhang, and   10.  Wang DY, Hong Y, Chen YG, et al., 2019, PEST-containing
               Xin-Ying Ji                                        nuclear protein regulates cell proliferation, migration, and
            Software: Salma S. Mahmoud, Hao-Jie Chen, Lei Qian, and   invasion in lung adenocarcinoma. Oncogenesis, 8(3): 1–14.
               Yangzhe Qin                                     11.  Wu DD, Gao YR, Li T,  et  al., 2018, PEST-containing
            Supervision: Dong-Dong Wu, Chun Yang Zhang, and Xin-  nuclear protein mediates the proliferation, migration, and
               Ying Ji                                            invasion of human neuroblastoma cells through MAPK
            Visualization: Salma S. Mahmoud, Hao-Jie Chen, Lei Qian,   and PI3K/AKT/mTOR signaling pathways. BMC Cancer,
                                                                  18(1): 1–15.
               and Yangzhe Qin
            Writing – original draft: Nazeer Hussain  Khan and      https://doi.org/10.1186/s12885-018-4391-9
               Wenkang Wang                                    12.  Dong P, Fu H, Chen L, et al., 2020, PCNP promotes ovarian
            Writing – review and editing: Tao Li, Muhammad Zubair,   cancer progression by accelerating β-catenin nuclear
               and Shazrul Fazry                                  accumulation and triggering EMT transition.  J  Cell Mol
                                                                  Med, 24(14): 8221–8235.
            References                                            https://doi.org/10.1111/jcmm.15491
            1.   Sigal A, Milo R, Cohen A, et al., 2006, Dynamic proteomics   13.  PDB Consortium, 2019, Protein data bank: The single global
               in individual human cells uncovers widespread cell-cycle   archive for 3D macromolecular structure data.  J  Nucleic
               dependence of nuclear proteins. Nat Methods, 3(7): 525–531.   Acids Res, 47(D1): D520–D528.
               https://doi.org/10.1038/nmeth892                14.  Wang J, Lisanza S, Juergens D, et al., 2021, Deep learning
            2.   Afzal A, Sarfraz M, Li GL,  et al., 2019, Taking a holistic   methods for designing proteins scaffolding functional sites.
               view of PEST-containing nuclear protein (PCNP) in cancer   bioRxiv, 2021: 468128.
               biology. Cancer Med, 8(14): 6335–6343.             https://doi.org/10.1101/2021.11.10.468128
               https://doi.org/10.1002/cam4.2465               15.  Jumper J, Evans R, Pritzel A, et al., 2021, Highly accurate
            3.   Chevaillier P, 1993, Pest sequences in nuclear proteins. Int J   protein structure prediction with AlphaFold.  Nature,
               Biochem, 25(4): 479–482.                           596(7873): 583–589.
            4.   Sarfraz M, Afzal A, Khattak S,  et al., 2021, Multifaceted   16.  Roy A, Kucukural A, Zhang Y, 2010, I-TASSER: A unified
               behavior of PEST sequence enriched nuclear proteins in   platform for automated protein structure and function
               cancer  biology  and  role  in  gene  therapy.  J  Cell Physiol,   prediction. Nat Protoc, 5(4): 725–738.
               236(3): 1658–1676.                                 https://doi.org/10.1038/nprot.2010.5
               https://doi.org/10.1002/jcp.30011               17.  Kim DE, Chivian D, Baker D, 2004, Protein structure
            5.   Yan J, Wang J, Zhang H, 2002, An ankyrin repeat-containing   prediction and analysis using the Robetta server.  Nucleic
               protein plays a role in both disease resistance and   Acids Res, 32(Suppl 2): W526–W531.
               antioxidation metabolism. Plant J, 29(2): 193–202.      https://doi.org/10.1093/nar/gkh468
               https://doi.org/10.1046/j.0960-7412.2001.01205.x  18.  Clementi C,  2021,  Fast track to  structural  biology.  Nat
            6.   Sekhar KR, Freeman M, 1998, PEST sequences in proteins   Chem, 13(11): 1032–1034.
               involved in cyclic nucleotide signalling pathways. J Recept      https://doi.org/10.1038/s41557-021-00814-y
               Signal Transduct Res, 18(2-3): 113–132.
                                                               19.  Pennisi  E,  2021,  Protein  structure  prediction  now  easier,
               https://doi.org/10.3109/10799899809047740          faster. Science, 373(6552): 262–263.


            Volume 1 Issue 1 (2022)                         10                      https://doi.org/10.36922/gpd.v1i1.65
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