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Gene & Protein in Disease Pre-metastatic niche oral cancer: Insights

Table 2. (Continued)
Term % P‑value Genes Fold enrichment Bonferroni Benjamini FDR
hsa00240: 1.51515152 0.0027625 DTYMK, UPP1, POLA2, 2.263550668 0.357643837 0.061272775 3.28513461
Pyrimidine POLR2D, PNP, NME7, TK1,
metabolism CMPK2, PRIM1, TYMS,
TYMP, POLE2, RRM2,
PRIM2, CDA, UCK2, NT5E
hsa04114: Oocyte 1.60427807 0.00518584 CDK1, PKMYT1, AURKA, 2.069877883 0.56477551 0.098762684 6.08511781
meiosis CDC20, PTTG1, ITPR3,
CCNE2, CCNB1, CCNE1,
PPP1CA, CCNB2, YWHAH,
MAD2L1, RPS6KA1, PLK1,
BUB1, FBXO5, CALML5
hsa05222: Small cell 1.3368984 0.00548348 COL4A2, COL4A1, RELA, 2.258795309 0.585121834 0.093126459 6.42383747
lung cancer SKP2, ITGA2, CDK6,
ITGA3, COL4A6, CCNE2,
CCNE1, LAMB3, ITGA6,
ITGAV, LAMC2, FN1
hsa05322: 1.42602496 0.01006257 HIST1H2BD, HIST1H2BE, 2.044323835 0.8017381 0.149402844 11.4957646
Systemic lupus HIST1H2AG, HIST1H2BF,
erythematosus HIST1H2BG, HIST1H2AE,
HIST1H2BH, ACTN1,
C1QC, C1QB, CD86,
HIST1H2BK, CD80,
HIST2H2BE, HIST1H2BI,
SNRPB, HIST1H3D,
HIST1H2AM, FCGR3B,
HIST1H4H
hsa04060: 2.85204991 0.01345636 CXCL1, CSF2, TNFRSF21, 1.544947021 0.885551997 0.178856747 15.0907417
Cytokine-cytokine CXCL5, OSMR,
receptor interaction TNFRSF12A, CXCL3,
TGFB3, CXCL9, CXCL6,
IL7R, CXCL11, CCL5, CCL4,
TGFB1, CXCL10, IL12RB2,
CCL20, IL1RAP, IL1B, IL1A,
IL2RB, TNFSF4, MET, IL24,
CCL18, CCL11, INHBA,
VEGFC, TNFSF10, CXCL13,
CXCL16
hsa05412: 1.15864528 0.01488495 ITGB4, ACTN1, ITGA2, 2.163688138 0.909236245 0.181234808 16.563565
Arrhythmogenic GJA1, ITGA3, CDH2,
right ventricular ITGA4, CACNA2D3, DSG2,
cardiomyopathy ITGA6, ITGA5, ITGAV,
ITGB6
hsa05020: Prion 0.71301248 0.01750244 C1QB, BAX, IL1B, STIP1, 2.891257996 0.940702468 0.195329275 19.2014569
diseases PRNP, CCL5, C1QC, IL1A
hsa04810: 2.31729055 0.03041059 DIAPH 3, ITGB4, ITGA2, 1.529677195 0.992854084 0.297383376 31.1268342
Regulation of actin ACTN1, ITGA3, ITGB2,
cytoskeleton ITGA4, MYH9, ARPC1A,
ARPC1B, NRAS, PFN1,
PPP1CA, PFN2, RAC2,
PAK2, ITGA6, ITGAX,
ITGA5, ITGAV, RRAS2,
ITGB6, CFL1, MSN, FN1,
F2R

(Cont’d...)

Volume 3 Issue 4 (2024) 6 doi: 10.36922/gpd.2971