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International Journal of Bioprinting Bioprinted cell-laden hydrogel for tracheal application

Figure 7. The anti-bacterial function of TETC in ICA/GelMA and ICA/CS/GelMA hydrogels after orthotopic tracheal transplantation in a rabbit
model. (a) The survival rates of experimental rabbits in ICA/GelMA and ICA/CS/GelMA groups over 8 weeks post-transplantation are presented. (b)
Gross observation of transplanted TETC in ICA/GelMA and ICA/CS/GelMA groups at 3 weeks is depicted, in which the red arrows indicate the interfaces
between the implanted trachea and the native trachea. (c) Immunofluorescence images of bacteria and COL II for transplanted TETC in ICA/GelMA
and ICA/CS/GelMA groups at 3 weeks are shown. (d–f) Quantitative measurements of (d) bacteria intensity, (e) COL II, and (f) Young’s modulus for
transplanted TETC in ICA/GelMA and ICA/CS/GelMA groups at 3 weeks are presented. Statistical analysis was conducted, and significance was indicated
by asterisks (*P < 0.05).

Volume 10 Issue 1 (2024) 171 https://doi.org/10.36922/ijb.0146