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International Journal of Bioprinting TPMS bone scaffold

Figure 9. Osteoprotegerin (OPG) staining results of cells cultured with different components. DAPI staining blue represents the nucleus, and green
represents the OPG gene. Notes: NC, negative control; ST, TPMS scaffold; IT, TPMS scaffold loaded with I-PRF; ST, TPMS scaffold loaded with SDF-1; SIT,
TPMS scaffold loaded with I-PRF and SDF-1.

of New Zealand white rabbits. Taken together, we have Investigation: Hong Zhu, Qifei Luan, Ziheng Lin
developed a semi-synthetic autologous bone grafting Writing – original draft: Hong Zhu, Meiyi Chen
biomaterial, which has tremendous clinical potential for Writing – review & editing: Xiaochuan Liu, Jinsi Wang,
mandibular defect repair to restore the facial morphology Kenny Man
and physiological function of patients.
Ethics approval and consent to participate
Acknowledgments
All animal surgical procedures were approved by
None. the Institutional Animal Care and Use Committee at
Guangdong Medical University (GDY2204012).
Funding
The study was supported by Guangdong Basic and Consent for publication
Applied Basic Research Foundation (2020B1515120001), Not applicable.
the Special Funds for Key Areas of Ordinary Universities
in Guangdong Province (2020ZDZX2013), Discipline Availability of data
Construction Project of Guangdong Medical University
(4SG23012G and 4SG23016G), Guangdong Medical Data can be obtained by contacting the corresponding
University Undergraduate Innovation Experiment Project author upon reasonable request.
(FYDS001, FYDS002, and FYDS003), and Guangdong
University Student Innovation Project (S20202170520, References
S202210571094, and S202210571046).
1. Chanchareonsook N, Junker R, Jongpaiboonkit L, Jansen
Conflict of interest JA. Tissue-engineered mandibular bone reconstruction for
continuity defects: A systematic approach to the literature.
The authors declare no conflicts of interest. Tissue Eng Part B Rev. 2014;20(2): 147–162.
doi: 10.1089/ten.TEB.2013.0131
Author contributions
2. Wong RC, Tideman H, Kin L, Merkx MAW. Biomechanics
Conceptualization: Jingying Zhang, Hong Zhu of mandibular reconstruction: A review. Int J Oral Maxillofac
Formal analysis: Yue Yang Surg. 2010;39(4): 313–319.
Funding acquisition: Jingying Zhang, Qifei Luan doi: 10.1016/j.ijom.2009.11.003

Volume 10 Issue 1 (2024) 473 https://doi.org/10.36922/ijb.0153