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International Journal of Bioprinting                               Liver printing: from structure to application




            Acknowledgments                                    4.   Macchi F, Sadler KC. Unraveling the epigenetic basis of
                                                                  liver development, regeneration and disease. Trends Genet.
            None.                                                 2020;36(8):587-597.
                                                                  doi: 10.1016/j.tig.2020.05.002
            Funding
                                                               5.   Matchett KP, Wilson-Kanamori JR, Portman JR, et al.
            This research was supported by the National Natural Science   Multimodal decoding of human liver regeneration. Nature.
            Foundation of China (62127811, U23A20453, U21A20396,   2024;630(8015):158-165.
            T2222029), the National Key Research and Development      doi: 10.1038/s41586-024-07376-2
            Program of China (2022YFA1104701), Initiative Scientific   6.   Sun T, Pikiolek M, Orsini V, et al. AXIN2<sup>+</sup>
            Research Program of Institute of Zoology (2023IOZ0101),   Pericentral hepatocytes have limited contributions to liver
            and the CAS Engineering Laboratory for Intelligent Organ   homeostasis and regeneration. Cell Stem Cell. 2020;26(1):97-
            Manufacturing (KFJ-PTXM-039).                         107.e6.
                                                                  doi: 10.1016/j.stem.2019.10.011
            Conflict of interest                               7.   Raasch  M, Fritsche E,  Kurtz A,  Bauer  M, Mosig  AS.
                                                                  Microphysiological systems meet hiPSC technology -
            The authors declare no conflicts of interest.         new tools for disease modeling of liver infections in basic
                                                                  research and drug development. Adv Drug Deliv Rev. 2019;
            Author contributions                                  140:51-67.
            Conceptualization:  Yifan Hou, Xin Liu, Shen Ji,      doi: 10.1016/j.addr.2018.06.008
               Xinhuan Wang                                    8.   Heymann  F,  Tacke  F.  Immunology in the  liver  — from
            Investigation: Yifan Hou                              homeostasis to disease.  Nat  Rev  Gastroenterol  Hepatol.
            Supervision: Qi Gu                                    2016;13(2):88-110.
            Visualization: Yifan Hou                              doi: 10.1038/nrgastro.2015.200
            Writing – original draft: Yifan Hou, Xin Liu       9.   Palakkan AA, Hay DC, PR Anil Kumar, TV Kumary, Ross
            Writing – review & editing: Yifan Hou, Xin Liu, Shen Ji,   JA. Liver tissue engineering and cell sources: issues and
               Xinhuan Wang, Qi Gu                                challenges. Liver Int. 2013;33(5):666-676.
                                                                  doi: 10.1111/liv.12134
            Ethics approval and consent to participate         10.  Prior N, Inacio P, Huch M. Liver organoids: from basic
                                                                  research to therapeutic applications.  Gut. 2019;68(12):
            Not applicable.
                                                                  2228-2237.
                                                                  doi: 10.1136/gutjnl-2019-319256
            Consent for publication
                                                               11.  Osonoi S, Takebe T. Organoid-guided precision hepatology
            Not applicable.                                       for  metabolic  liver  disease.  J Hepatol.  2024;80(5):
                                                                  805-821.
            Availability of data                                  doi: 10.1016/j.jhep.2024.01.002

            Not applicable.                                    12.  Panwar A, Das P, Tan LP. 3D hepatic organoid-based
                                                                  advancements in LIVER tissue engineering. Bioengineering
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            Volume 10 Issue 5 (2024)                       143                                doi: 10.36922/ijb.3819
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