Page 253 - IJB-10-5
P. 253

International Journal of Bioprinting                                  3D printed hydrogels for tumor therapy




               Figure 8C–E graphically represents the changes of   be similar. The pH of GelMA, HAp/GelMA, MgHAp/
            pH value, Ca , and Mg  in PBS after soaking GelMA,   GelMA,  and MgHAp/GelMA-PDA  hydrogels reduced
                                2+
                       2+
            HAp/GelMA, MgHAp/GelMA, and MgHAp/GelMA-           on the first day, followed by an increase in the next 13
            PDA hydrogels in PBS for 2 weeks. As shown in      days. The Ca  release profiles in Figure 8D indicated that
                                                                         2+
            Figure 8C, the change of pH of hydrogels appeared to   printed HAp/GelMA, MgHAp/GelMA, and MgHAp/































































            Figure 6. Morphology and structure of 3D-printed hydrogels. (A) Optical images showing the morphology and structure of GelMA, HAp/GelMA,
            MgHAp/GelMA, and MgHAp/GelMA-PDA hydrogels after 3D printing. (B) Printability values of GelMA, HAp/GelMA, MgHAp/GelMA, and MgHAp/
            GelMA-PDA inks. (C) Struct diameter expansion rates of GelMA, HAp/GelMA, MgHAp/GelMA, and MgHAp/GelMA-PDA hydrogels. (D) Surface
            and cross-sectional morphology of 3D-printed GelMA, HAp/GelMA, MgHAp/GelMA, and MgHAp/GelMA-PDA hydrogels and EDS mapping images
            showing the element distribution in the MgHAp/GelMA hydrogel.


            Volume 10 Issue 5 (2024)                       245                                doi: 10.36922/ijb.3526
   248   249   250   251   252   253   254   255   256   257   258