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International Journal of Bioprinting 3D-Printed Zn/MgHA-PCL for angio/osteogenesis

Figure 4. Evaluation of the angiogenic ability of HA-PCLs, 10Zn@HA-PCLs, 5Mg10Zn@HA-PCLs, 10Mg10Zn@HA-PCLs, and 15Mg10Zn@HA-PCLs in
vitro. (A) Proliferative activity of HUVECs in each group of scaffolds after 24, 48, and 72 h of culture. (B) Statistical results of wound healing. (C) Live/dead
staining images of each group of scaffolds. (D) Wound healing assay of HUVECs in the presence of each group of scaffolds (scale bars = 400 μm). (E) The
angiogenesis-related gene expression of each group of scaffolds (VEGF, FLT1, KDR, and bFGF). *p < 0.05, ** p < 0.01, *** p < 0.001; n = 4. Scale bars: 500
μm (C); 100 μm (D). Abbreviations: HA, hydroxyapatite; HUVECs, human umbilical vein endothelial cells; PCL, polycaprolactone.

Volume 10 Issue 6 (2024) 292 doi: 10.36922/ijb.4243