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International Journal of Bioprinting                              Design and property of PLPG/PDLA scaffold



































            Figure 6. Osteosynthesis induction in MC3T3-E1 cells co-cultured on the PLPG/PDLA scaffolds. (a) Alkaline phosphatase (ALP) staining of PLPG/
            PDLA scaffolds for 14 days. (b) Quantitative analysis of MC3T3-E1 cells co-cultured on PLPG/PDLA scaffolds for 14 days (n = 3). Abbreviations: PDLA:
            Poly(D-lactic acid); PLPG: PLLA-ran-PDO-ran-GA.


            and  the  National  Natural  Science  Foundation  of  China-  Availability of data
            Young Scientists Fund (No. 81600867).
                                                               The data presented in this study are available upon request
            Conflict of interest                               from the corresponding author.
            The authors declare that they have no competing interests.  References

            Author contributions                               1.   Chen Y, Huang J, Liu J, et al. Tuning filament composition
                                                                  and  microstructure  of  3D-printed  bioceramic  scaffolds
            Conceptualization: Tiantang Fan, Dongya Liu           facilitate bone defect regeneration and repair.  Regen
            Data curation:  Tiantang Fan, Xiao Meng, Jingwen Qin,   Biomater. 2021;8:rbab007.
               Ruishen Zhuge                                      doi: 10.1093/rb/rbab007
            Formal analysis: Tiantang Fan, Xiao Meng, Jingwen Qin,   2.   Wei S, Ma J, Xu L, et al. Biodegradable materials for bone
               Ruishen Zhuge, Ruishen Zhuge                       defect repair. Military Med Res. 2020;7:1-25.
            Funding: Tiantang Fan, Jianru Liu                     doi: 10.1186/s40779-020-00280-6
            Investigation: Tiantang Fan                        3.   Xu L, Ma F, Leung FK, et al. Chitosan-strontium chondroitin
            Methodology: Yutong Wang, Chunyu Zhang, Yiqiao Yin    sulfate scaffolds for reconstruction of bone defects in aged
            Resources: Jianru Liu, Tianyun Fan                    rats. Carbohyd Polym. 2021;273:118532.
            Supervision: Tianyun Fan, Dongya Liu                  doi: 10.1016/j.carbpol.2021.118532
            Writing – original draft: Tiantang Fan             4.   Cendrero AM, Martínez FF, Requejo WGS, et al. Open-
            Writing – review & editing: Tianyun Fan, Dongya Liu   source library of tissue engineering scaffolds. Mater Design.
                                                                  2022;223:111154.
            Ethics approval and consent to participate            doi: 10.1016/j.matdes.2022.111154
                                                               5.   Wang C, Huang W, Zhou Y, et al. 3D printing of bone tissue
            Not applicable.
                                                                  engineering scaffolds. Bioact Mater. 2020;5:82-91.
                                                                  doi: 10.1016/j.bioactmat.2020.01.004
            Consent for publication
                                                               6.   Asghari F, Faradonbeh DR, Malekshahi ZV, et al. Hybrid
            Not applicable.                                       PCL/chitosan-PEO nanofibrous scaffolds incorporated with

            Volume 10 Issue 6 (2024)                       541                                doi: 10.36922/ijb.4645
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