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International Journal of Bioprinting                            Biomechanical analysis of mandibular implants




                 future research is essential to ensure the internal   Conflict of interest
                 integrity of the specimens and accurately assess their
                 mechanical performance. In addition, future studies   All authors declare that they have no conflict of interest.
                 should involve more comprehensive analyses, such   Author contributions
                 as dynamic occlusion tests, animal experiments,
                 and even clinical research, to explore the long-term   Conceptualization: Lih-Jyh Fuh, Heng-Li Huang
                 usability and success rate of mandibular implants in   Data curation: Hao Zhang
                 animals or humans.                            Formal analysis: Hao Zhang
                                                               Funding acquisition: Heng-Li Huang
            5. Conclusion                                      Investigation: Hao Zhang, Heng-Li Huang
                                                               Methodology: Hao Zhang, Heng-Li Huang
            Compared with the tetrahedron and hex-star lattice   Project administration: Heng-Li Huang
            designs, the quad-diametral-cross and hex-vase designs   Resources: Lih-Jyh Fuh
            exhibited fewer high-stress regions. According to the  in   Software: Jui-Ting Hsu, Lih-Jyh Fuh
            vitro  experimental results, when  the  rod diameter of  the   Supervision: Heng-Li Huang
            lattice structure increased, the overall elastic modulus of   Validation: Jui-Ting Hsu, Heng-Li Huang
            the structure significantly increased. Regardless of whether   Writing – original draft: Hao Zhang, Heng-Li Huang
            quad-diametral-cross  or hex-vase design was used, the   Writing – review & editing:  Hao Zhang, Zhe-Min Lim,
            maximum stress observed in the mandibular implant did   Heng-Li Huang
            not exceed the yield strength of Ti6Al4V (910 MPa). These
            findings indicate that the proposed mandibular implant   Ethics approval and consent to participate
            was not at risk of plastic deformation or immediate failure.
            When the elastic modulus of the mandibular implant   The study was conducted according to the guidelines of the
            decreased, the frictional stress observed at the interface   Declaration of Helsinki and approved by the Institutional
            between the abutment and the implant increased, which   Review Board of China Medical University Hospital
            presumably increased the risk of interface wear. In addition,   (protocol code: CMUH110-REC2-247).
            the maximum strain observed in the surrounding bone of   Consent for publication
            the mandibular implant was within 1500–3000 µstrain.
            These results indicate that, in the presence of appropriate   Not applicable.
            occlusal forces, the proposed mandibular implant did not
            cause immediate damage and promoted growth of the   Availability of data
            surrounding bone. However, there are still some limitations   The datasets generated and/or analyzed in this study
            in this study, particularly in the final step where the finite   are  available  from  the  corresponding author  upon
            element simulation of the mandibular implants was   reasonable request.
            conducted using only the material properties of different
            lattice structures for biomechanical analysis. In this regard,   References
            future research can incorporate the actual 3D structure of
            the lattice into the finite element model for more advanced   1.   Seikaly H, Chau J, Li F, et al. Bone that best matches the
            analysis, as well as include in vitro or animal experiments to   properties of the mandible. J Otolaryngol. 2003;32(4):262-265.
            verify the clinical applicability of the findings. Additionally,      doi: 10.2310/7070.2003.41646
            simulating the biomechanical properties of the implant   2.   Bak M, Jacobson AS, Buchbinder D, Urken ML.
            warrants further evaluation through  in vitro testing and   Contemporary reconstruction of the mandible. Oral Oncol.
            printing of its final configuration.                  2010;46(2):71-76.
                                                                  doi: 10.1016/j.oraloncology.2009.11.006
            Acknowledgments                                    3.   Schlueter B, Kim KB, Oliver D, Sortiropoulos G. Cone beam
            None                                                  computed tomography 3D reconstruction of the mandibular
                                                                  condyle. Angle Orthod. 2008;78(5):880-888.
                                                                  doi: 10.2319/072007-339.1
            Funding
                                                               4.   van Baar GJC, Forouzanfar T, Liberton NPTJ, Winters
            This study was supported by the Ministry of           HAH, Leusink FKJ. Accuracy of computer-assisted
            Science  and  Technology,  Taiwan  (Project  No.      surgery in mandibular reconstruction: a systematic review.
            MOST 111-2221-E-039-008-MY2).                         Oral Oncol. 2018;84:52-60.

            Volume 10 Issue 6 (2024)                       579                                doi: 10.36922/ijb.3943
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