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REVIEW ARTICLE

           3D Printing Technologies in Metallic Implants: A

           Thematic Review on the Techniques and Procedures


           Shokouh Attarilar , Mahmoud Ebrahimi , Faramarz Djavanroodi , Yuanfei Fu ,
                              1,2
                                                                                             6
                                                     3
                                                                               4,5
           Liqiang Wang *, Junlin Yang *
                                        1
                         2
           1 Department of Pediatric Orthopaedics, Xinhua Hospital Affiliated to Shanghai Jiao Tong University, School of Medicine,
           Shanghai, China
           2 State Key Laboratory of Metal Matrix Composites, School of Material Science and Engineering, Shanghai Jiao Tong
           University, Shanghai, China
           3 National Engineering Research Center of Light Alloy Net Forming, School of Materials Science and Engineering, Shanghai
           Jiao Tong University, Shanghai, China
           4 Department of Mechanical Engineering, College of Engineering, Prince Mohammad Bin Fahd University, Al Khobar, KSA
           5 Department of Mechanical Engineering, Imperial College London, London, UK
           6 Ninth People’s Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200011, China

           Abstract: Additive manufacturing (AM) is among the most attractive methods to produce implants, the processes are very swift
           and it can be precisely controlled to meet patient’s requirement since they can be produced in exact shape, dimension, and even
           texture of different living tissues. Until now, lots of methods have emerged and used in this field with diverse characteristics. This
           review aims to comprehensively discuss 3D printing (3DP) technologies to manufacture metallic implants, especially on techniques
           and procedures. Various technologies based on their main properties are categorized, the effecting parameters are introduced, and
           the history of AM technology is briefly analyzed. Subsequently, the utilization of these AM-manufactured components in medicine
           along with their effectual variables is discussed, and special attention is paid on to the production of porous scaffolds, taking
           pore size, density, etc., into consideration. Finally, 3DP of the popular metallic systems in medical applications such as titanium,
           Ti6Al4V, cobalt-chromium alloys, and shape memory alloys are studied. In general, AM manufactured implants need to comply
           with important requirements such as biocompatibility, suitable mechanical properties (strength and elastic modulus), surface
           conditions, custom-built designs, fast production, etc. This review aims to introduce the AM technologies in implant applications
           and find new ways to design more sophisticated methods and compatible implants that mimic the desired tissue functions.
           Keywords: Additive manufacturing; 3D printing techniques; Biometals; Implants; Porous scaffolds


           *Correspondence to: Liqiang Wang, State Key Laboratory of Metal Matrix Composites, School of Material Science and Engineering, Shanghai
           Jiao Tong University, Shanghai, China; wang_liqiang@sjtu.edu.cn. Junlin Yang, Department of Pediatric Orthopaedics, Xinhua Hospital Affiliated
           to Shanghai Jiao Tong University, School of Medicine, Shanghai, China; yjunlin@126.com
           Received: August 28, 2020; Accepted: October 16, 2020; Published Online: December 9, 2020

           Citation: Attarilar S, Ebrahimi M, Djavanroodi F, et al., 2021, 3D Printing Technologies in Metallic Implants: A Thematic
           Review on the Techniques and Procedures. Int J Bioprint, 7(1): 306. http://doi.org/10.18063/ijb.v7i1.306

           1. Introduction                                     with rapid healing time,  fast preparation  of implants,

           As  the  world’s  elderly  population  grows,  the  need  for   and  custom-built  implants  that  are  tailored  to  patients’
           medical implants is rapidly growing. It is expected that   fracture  conditions.  Furthermore,  avoiding  possible
           the number of people aged 65 or above will increase to   subsidiary issues arise from low-quality designs, stress-
           about  20%  of  the  world  population  by  2050 .  These   shielding  effects,  and  infections.  The  traditionally
                                                   [1]
           elderly patients and other patients with bone fracture and   manufactured implants have a lot of limitations, such as
           failures need special cares, specifically those associated   a time-consuming production process, low capability in
           © 2020 Attarilar, et al. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International
           License (http://creativecommons.org/licenses/by-nc/4.0/), permitting all non-commercial use, distribution, and reproduction in any medium, provided the
           original work is properly cited.
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