Page 162 - IJB-8-1

Design Criteria for Patient-Specific Mandibular Implant
Table 9. Results of finite element simulations of mandibular large defect repaired with solid and parametric reconstruction implants.
Weight Maximum von Mises Stress (MPa) Maximum principal stress
(g) (implant) (MPa) (remaining bone)
Segment C Solid 27.95 18.45 51
model

Parametric 12.76 19.43 50
model

Variation between solid and parametric −54.3% 5.3% −2%
model
Segment B Solid 45.08 235.61 68.14
model

Parametric 16.35 230 56.59
model

Variation between solid and parametric −63.7% −8.2% −17%
model
Segment A+B Solid 85.91 285 88.6
model

Parametric 26 271 88.5
model

Variation between solid and parametric −69.7% −5% 0%
model

also be found in Tables 7 (3 column) and 9 (3 column). defective mandible is an important surgery. The long-
rd
rd
The biomechanical fatigue test results are listed and shown term survival rate for this surgery has gradually improved
in Table 8. All cases using the AM reconstructed implant in recent years due to the advent of chemotherapy
can pass the 250,000 dynamic load level without causing and radiotherapy target drugs. Nevertheless, further
damage to the samples. However, the damaged locations integrated engineering technologies, such as image
can be found in the condyle head of the mandible, bone processing, CAD, FE analysis, and optimization analysis
plate fracture, and bone screw loosening for the five cases for structural design and AM manufacturing to improve
of C/B/A+B/B+C/B+C+B when using traditional bone the appearance and prosthesis requirements for large
plates. mandibular reconstructed implants are necessary.
According to FDA regulations, it is not possible
4. Discussion to perform SE fatigue test comparison for a single
Oral cancer-induced continuity defect in the mandible mandible defect region for a specific patient. To enable
is a very troublesome or complicated disease in Asia, specific patient clinical application design criterion
especially in Taiwan. Effectively reconstructing the for reconstructed implants in the future and meet the

148 International Journal of Bioprinting (2022)–Volume 8, Issue 1