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     CFD Assessment of Extrusion Bioprinting Parameters
                        A                                    B
           Figure 11. Variation of (A) outlet velocity (m/s) and (B) outlet pressure (Pa) in the nozzle against time (s) for different printing speeds
           through transient simulation.
           A                                                 B
                              C
           Figure 12. Surface plot for maximum wall shear stress (in kPa) for (A) tapered conical, (B) conical, and (C) cylindrical nozzles.
           nozzle, the computational relationship suffers due to the     MWSS  =  1.26 3.56x+  −  1.29y −
           wide variations  in the MWSS (abbreviated  as MWSS        tapered                                (3)
           in the following equations) due to the effect of a drastic   7.11x −  2  1.12xy +  1.02y 2
           increase  in  flow  rate  to  maintain  the  constant  inlet
           pressure condition. As such, at low values of pressure and   MWSS  =  0.92 8.27x+  +  0.059y −
           diameter, the model predicts a negative MWSS, as shown    2 conical      2                       (4)
           in Figure 12C.                                      17.48x −  2.76xy −  0.74y
           54                          International Journal of Bioprinting (2022)–Volume 8, Issue 2
     	
