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International Journal of Bioprinting  Evaluation of advanced visual computing solutions for the left atrial appendage occlusion


              The VR VRIDAA platform was the technology with a   3.3. Open questions on each technology
            wider range of answers from the participants regarding   Figure 7 summarizes the answers from participants to the
            its use daily, with one strongly agreeing to use it and the   open questions on each evaluated technology, focusing
            remaining ones with no clear opinion. Moreover, there   on their incorporation into the clinical workflow. Three
            was no agreement in the participants on any major flaw   physicians (all imaging cardiologists, not interventionists)
            of the technology. Five participants consider it easy to   would add the VIDAA platform into the clinical workflow,
            use, although three of them reported that they might   one of them only for planning complex anatomies and the
            need support at some point. Participants also mentioned   two remaining would include also the platform for their
            that the devices recommended by the VRIDAA system   regular cases. The VR platform, VRIDAA, was included
            were slightly bigger than expected. Finally, according   in the workflow by only 2/6 clinicians; both used it for
            to the participants, most of them were confident with   regular and complex planning, while half of the participants
            the device positioning due to the possibility of freely   would use 3D printing. However, 5/6 participants found the
            moving.                                            3D-printed models very useful for exploring the anatomy
              The visualization of in silico fluid simulations was the   and were willing to use this technology in a frequent
            technology with the lowest score (58.27), barely passing   basis, provided the printer and flexible materials would be
            the usability test, in the low marginal area of acceptability   cheaper. Despite the low values in the SUS questionnaire,
            ranges. However, it was the technology presenting the   4/6 clinicians (including the three imaging ones) would use
            largest variance between participants (from 77.6 to   in silico fluid simulations for planning complex anatomies,
            28.8), some evaluating it at the level of the remaining   mainly to avoid leaks and device-related thrombus (DRT)
            technologies and others in the not acceptable usability   after LAAO device implantation. It is worthy to point out that
            area. Furthermore, five participants would like to use the   in silico fluid simulations are the only technology positively
            technology frequently, with the remaining one providing   rated for follow-up purposes (2/6 participants), especially if
            an inconclusive answer. Moreover, they found most of the   the relationship between low blood flow velocities and DRT
            simulation-based features useful, especially in identifying   is confirmed in more extensive clinical studies.
            possible leaks after LAAO implantation, which is well   One participant (P1) was from a hospital where CT
            integrated and without inconsistencies, and they felt   is not routinely used for LAAO planning; US imaging
            quite confident on its use at the end of the practical   is preferred since most patients are elderly people with
            session. The main reason for the overall low score was   other comorbidities (e.g., renal dysfunction), often having
            the poor easiness of use of the Ansys Discovery Live   contraindications to CT acquisition. However, the same
            interface; almost all participants required support and   physician would be interested in acquiring CT scans to
            claimed that it is difficult to learn the interface, which is   have access to the evaluated computing technologies when
            also cumbersome to use.                            younger patients are eligible for LAAO implantation.



























            Figure 7. Ideal workflow according to the participants. On the left, gray shading represents imaging cardiologists, white shading represents interventional
            cardiologists.


            Volume 9 Issue 1 (2023)                        267                      https://doi.org/10.18063/ijb.v9i1.640
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