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International Journal of Bioprinting  Evaluation of advanced visual computing solutions for the left atrial appendage occlusion


            together with the full range of 3D-printed replicas of the   A              B
            Amplatzer Amulet and Watchman FLX LAAO devices
            available in the market. Physicians could then interact with
            both types of 3D-printed models to decide which device
            would fit each LA anatomy better.
            2.4.4. Virtual reality VRIDAA platform
            The tasks performed by the participants on the VRIDAA
            platform were very similar to VIDAA. Nevertheless, the
            LAA centerline was already provided by default. Once the
            participant wore the VR glasses, the LA appeared, together   C              d
            with its centerline, and the physician could move it, grab it,
            or go inside to better explore the interior of the anatomical
            structure. Then, the user could select the type and size of
            a given device, which would be placed at the beginning of
            the centerline, which was able to move along. In addition,
            the LAAO device could also be grabbed and moved freely.
            2.4.5. In silico simulations
            Initially, the participant was asked to select a device
            type  and  size,  after  which  it could be  freely placed  in
            any location of the LAA using the interface of the Ansys
            Discovery Live software. The LA anatomy could also be
            moved. Once a device position was chosen, the simulation   Figure 5.  (A‑D)  Examples of  in silico fluid simulations using Ansys
                                                               Discovery Live with optimal device settings according to a given
            was launched, requiring several minutes to visualize the   participant. 3D streamline-based visualization simulations were used to
            resulting blood flow patterns (Figure 5). Therefore, blood   illustrate blood flow patterns of in the left atrium and left atrial appendage.
            flow velocities near the device could be estimated, as well   Blue and  red represent low velocity (<  10 m/s) and  high velocities (>
            as flow recirculations and leaks due to the chosen LAAO   20 m/s), respectively.
            positioning, potentially leading to DRT.
                                                               •   Have you tested any of these technologies before? If
            2.4.6. Evaluation questionnaires                      yes, which one?
                                                               •   Have  you  participated  in  the  development  of  these
            Once the participants had gone through all the patients,   technologies? If yes, which one?
            they answered two questionnaires: A SUS questionnaire   •   Which technologies would you add in your ideal
            and a more general questionnaire with open questions.   workflow for LAAO (disregarding economical and
            The SUS questionnaire, developed by Brooke , was used   equipment restrictions)?
                                                [38]
            to give a more quantitative assessment on the usability of   •   Which  technology did  influence  your  final  decision
            the technologies. It is a 10-item questionnaire using, in our   on device election the most?
            case, a 7-point Likert scale. Consequently, the physicians   •   If your hospital is mainly using ultrasound (US)
            answered the SUS questionnaire for each technology    imaging to plan LAAO interventions instead of CT,
            at the end of the session. Details on the SUS questions   would you consider acquiring CT data only to be able
            and the answers for each technology are included in the   to use these technologies?
            Supplementary File.
              The aim of the questionnaire with open questions was   3. Results
            to profile the participants and to know more about how   3.1. Participant profile
            these technologies could be implemented in their current   Out of the six participants, three were interventional
            workflow, according to their point of view. The questions   cardiologists (P2, P3, and P4), that is, physicians who
            were the following:
                                                               are implanting the device, while the remaining three are
            •   Years of experience in LAAO interventions.     imaging cardiologists, who were responsible for the medical
            •   Current position at the hospital.              image acquisition and analysis before and during LAAO
            •   Did you know about the application of these    procedures. On average, they had 5.08 years of experience
               technologies to LAAO planning? If yes, which one?  in LAAO interventions (with 10 years and < 1 year for the


            Volume 9 Issue 1 (2023)                        265                      https://doi.org/10.18063/ijb.v9i1.640
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