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International Journal of Bioprinting                    Fabrication of 3D functional hydrogel for wound dressings





























































            Figure 8. The morphological observation of L929 fibroblasts on the hydrogels by SEM and cytotoxicity test of the hydrogels. (a) The SEM images of fi-
            broblasts cultured on the hydrogels for 1, 4, and 7 days (500× magnification, scale bar: 20 μm) and the enlarged images of fibroblasts for 7 days (1000×
            magnification, scale bar: 20 μm). (b) Cell survival ratio on the hydrogels tested by CCK-8. Data are expressed as mean ± SD. NS: p > 0.05; * p < 0.05,
            ** p < 0.01, *** p < 0.001.

            superior biocompatibility based on live and dead staining   Funding
            test, SEM images and CCK-8 assay. The strategy of combining   This work was supported by the National Natural Science
            the advantages of 3D printing and several biocompatible   Foundation of China (31670978/32000977), the Fok
            materials in this study provided an inspiration for the design   Ying Tung Education Foundation (132027), the State
            of multifunctional dressing for wound healing.
                                                               Key Laboratory of Fine Chemicals (KF1111), and the
            Acknowledgments                                    Fundamental Research Funds for the Central Universities
                                                               (DUT20ZD206/ DUT21YG113/DUT22YG213) and Natural
            None.                                              Science Foundation of Shandong Province (ZR2020QH188).




            Volume 9 Issue 2 (2023)                        448                          https://doi.org/10.18063/ijb.689
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