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International Journal of Bioprinting                          Lattice-Solid hybrid 3D printing for artificial implant



            cooling rates of the mesh structures, thereby increasing the   Writing – original draft: Jong Woong Park, Eunhyeok Seo,
            tensile strength of the specimen. In addition, the results   Hyokyung Sung, Im Doo Jung
            of the fractographic analysis of P- and S-type specimens   Writing – review & editing: Jong Woong Park, Eunhyeok
            with the same mesh volume fraction indicate that the high   Seo, Hyun Guy Kang, Hyokyung Sung, Im Doo Jung
            strength of the S-type specimen was achieved by the large
            volume fraction of the stage 1 area, where deep and clear   Ethics approval and consent to participate
            dimples were observed.                             Regarding the patient presented in  Figure 1, this study

               Through patient-specific orthopedic implants with   protocol has been approved by the institutional review
            an  optimized  volume  fraction  of  the  lattice  structure,   board of National Cancer Center (NCC2017-0129). The
            mechanical performance for repeated weight loading was   present study was conducted according to the principles of
            improved, and guidelines for implant design could be   the Declaration of Helsinki. Written informed consent was
            established. However, it is necessary to devise definitive   obtained from a participant prior to inclusion in the study.
            implant designs that are clinically safe, and thus provide
            a range of clear volume fractions of lattice structures.   Consent for publication
            Moreover, further works on fatigue behavior upon repetitive   Not applicable.
            loads applied to the lower limbs are also necessary. These
            results and continuous research can provide a better basis   Availability of data
            for effective enhancement of mechanical performance and
            optimized safe designs.                            Not applicable.

            Acknowledgments                                    References

            None.                                              1.   Mankin H, Gebhardt M, Jennings L, et al., 1996, Long-term
                                                                  results of allograft replacement in the management of bone
            Funding                                               tumors. Relat Res, 324:86–97.
            This work was supported by the Technology Innovation   2.   Wunder J, Leitch K, Griffin A,  et al., 2001, Comparison
            Program (grant no. 20017502) funded by the Ministry   of two methods of reconstruction for primary malignant
                                                                  tumors at the knee: A sequential cohort study. J Surg Oncol,
            of  Trade,  Industry  &  Energy  (MOTIE,  Korea),  the   77:89–99.
            National Research Foundation of Korea (NRF) grant
            funded by the Korea government (MSIT) (grant no.      https://doi.org/10.1002/jso.1076
            2021M2D2A1A01050059, 2020R1C1C1006214), and the    3.   Jeon  DG,  Kim  MS,  Cho  WH,  et al.,  2007,  Pasteurized
            research grant funded by the National Cancer Center of   autograft for intercalary reconstruction. Clin Orthop Relat
            the Republic of Korea (grant no. 2110270).            Res, 456:203–210.
                                                                  https://doi.org/10.1097/BLO.0b013e31802e7ec8
            Conflict of interest
                                                               4.   Jeon DG, Song WS, Cho WH,  et al., 2014, Overlapping
            The authors declare that they have no known competing   allograft for primary or salvage bone tumor reconstruction.
            financial interests or personal relationships that could have   J Surg Oncol, 110:366–371.
            appeared to influence the work reported in this paper.  https://doi.org/10.1002/jso.23669
                                                               5.   Shusteff M, Browar AEM, Kelly EW, et al., 2017, One-step
            Author contributions                                  volumetric additive manufacturing of complex polymer
            Conceptualization: Jong Woong Park, Eunhyeok Seo,     structures. Sci Adv, 3:eaao5496.
               Hyokyung Sung, Im Doo Jung                         https://doi.org/10.1126/sciadv.aao5496
            Formal analysis: Jong Woong Park, Eunhyeok Seo, Haeum   6.   Zhang D, Qiu D, Gibson MA,  et al., 2019, Additive
               Park, Ye Chan Shin, Hyokyung Sung, Im Doo Jung     manufacturing of ultrafine-grained high-strength titanium
            Funding acquisition: Hyokyung Sung, Im Doo Jung       alloys. Nature, 576:91–95.
            Investigation: Jong Woong Park, Eunhyeok Seo, Haeum   https://doi.org/10.1038/s41586-019-1783-1
               Park, Ye Chan Shin
            Methodology: Haeum Park, Ye Chan Shin, Hyun Guy Kang  7.   Jung ID, Choe J, Yun J,  et al., 2019, Dual speed laser re-
            Supervision: Hyokyung Sung, Im Doo Jung               melting for high densification in H13 tool steel metal 3D
            Visualization: Jong Woong Park, Eunhyeok Seo, Hyun Guy   printing. Arch Metall Mater, 64(2):571–578.
               Kang                                               https://doi.org/10.24425/amm.2021.136388


            Volume 9 Issue 4 (2023)                         26                         https://doi.org/10.18063/ijb.716
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