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International Journal of Bioprinting                                   3D printing and bioprinting in urology




                                                               (micro-CT) or magnetic resonance imaging (MRI). Then,
                                                               the 3D digital model of the target object is obtained by
                 Publications  105,891  531                    reconstruction, design, and repair using computer-aided
                                                               design (CAD) software and exported in STL or IGES file
                                         73
                                                               format for subsequent 3D printing. Next, the appropriate
                                                               3D printer and printing materials are selected based on the
                                    OR “adrenal gland” ) ) OR ( AB = ( urology OR nephrology OR prostate OR kidney OR ureter OR bladder OR urethra OR penile OR penis OR “adrenal
                                             urethra OR penile OR penis OR “adrenal gland” ) ) OR ( AB = ( urology OR nephrology OR prostate OR kidney OR ureter OR bladder OR urethra OR
                                  “biofabricat*” OR “bioplott*” ) AND ( ( TI = ( urology OR nephrology OR prostate OR kidney OR ureter OR bladder OR urethra OR penile OR penis
                                           writing” OR “bioprint*” OR “biofabricat*” OR “bioplott*” ) AND ( ( TI = ( urology OR nephrology OR prostate OR kidney OR ureter OR bladder OR
                                                               part’s purpose and processing accuracy. Finally, the digital
                                         TS=( ( ( “3D” OR “3-D” OR “three dimensional” OR “3-dimensional” ) AND ( “bioprint*” OR “biofabricat*” OR “biomanufactur*” ) ) OR “direct ink
                                                               model is imported into the 3D printer for fabrication. It
                        bed fusion” OR “binder jetting” OR “mate-rial extrusion” OR “direct ink writing” OR “material jetting” OR “rapid prototype*” OR “bioprint*” OR
                                bed fusion” OR “binder jetting” OR “mate-rial extrusion” OR “direct ink writing” OR “material jetting” OR “rapid prototype*” OR “bioprint*” OR
                      manufacturing” OR “stereolithography” OR “fused deposition modeling” OR “selective laser sintering” OR “selective laser melting” OR “powder
                              manufacturing” OR “stereolithography” OR “fused deposition modeling” OR “selective laser sintering” OR “selective laser melting” OR “powder
                                                               is important to note that some printing methods require
                                                               post-processing for printed samples. 3D printing can be
                    TS=( ( ( “3D” OR “3-D” OR “three dimensional” OR “3-dimensional” ) AND ( “print*” OR “fabricat*” OR “manufactur*” ) ) OR “additive
                            TS=( ( ( “3D” OR “3-D” OR “three dimensional” OR “3-dimensional” ) AND ( “print*” OR “fabricat*” OR “manufactur*” ) ) OR “additive
                                                               divided into different categories according to its working
                                                               principle and applicable materials, mainly including
                                                               stereolithography (SLA) [19-21] , DLP [2,11,22] , FDM [11,23,24] , direct
                                                               ink writing (DIW) [25-31]  (through which the printed material
                                                               is a series of lines or droplets), material jetting (MJ) ,
                                                                                                           [32]
                                                               binder jetting (BJ) [33-35] , selective laser sintering (SLS) [36,37] ,
                                                               and selective laser melting (SLM) [38-41]  (Figure 5). The
                                                               characteristics,  materials,  advantages, and  disadvantages
                                               penile OR penis OR “adrenal gland” ) ) ) AND DOP=(2013-01-01/2022-12-31) AND DT==("ARTICLE")
                                                               of these different types of 3D printing technologies are
                                                               demonstrated in Table 2.
                                                  Booleans: AND, OR, and NOT; TS = topic subject; TI = title; AB = abstract; DOP = publication date; DT = document types.
                          “biofabricat*” OR “bioplott*” ) AND DOP=(2013-01-01/2022-12-31) AND DT==("ARTICLE")
                                                                  In detail, SLA technology uses an oscillating mirror system
                                                               to control the ultraviolet (UV) laser (355 nm or 405 nm)
                                                               spot scanning crosslinking to achieve the curing of resin
                                                               materials, which has better mechanical properties but less
                                                               applicable materials, poor processing accuracy, and slow
                                      gland” ) ) ) AND DOP=(2013-01-01/2022-12-31) AND DT==("ARTICLE")
                                                               processing speed (Figure 5A). Moreover, the incomplete
                                                               crosslinked resin is toxic, which is a shortcoming. Based on
                                                               SLA technology, scientists developed a DLP system based on
                                                               a digital mirror device and photosensitive polymers liquid,
                                                               which has high precision and fast fabrication (Figure 5B).
                                                               Moreover, with the rapid development of DLP, it is able to
                                                               perform biofabrication of organs and tissues, such as heart
             Table 1. The search strategies used in this paper and their details
                                                               and blood vessels, for potential future applications. In
                                                               contrast to the previous two 3D printing technologies that
                                                               employ liquids, FDM technology, one of the most widely
                                                               used 3D printing technologies, utilizes solid polymer
                                                               wire as the raw material (e.g., polylactic acid [PLA],
                                                               acrylonitrile butadiene styrene [ABS], poly-ε-caprolactone
                                                               [PCL]), which is melted by heating and then stacked
                                                               layer by layer to build 3D-printed samples (Figure  5C).
                                                               The common heating temperature of this technology is
                 Query preview                                 PCL, which has been approved by the US Food and Drug
                                                               50–280°C, which can generally melt most of the polymers.
                                                               Administration (FDA), is used in tissue engineering areas
                                                               including bone tissue engineering and meniscal tissue
                                                               engineering. Although this technology is widely used in
                                                               crafts, polymer parts, tissue engineering scaffolds, etc., its
                    “3D printing” (#1)  “3D printing” AND   “urology” (#2)  “3D bioprinting”   AND “urology” (#3)  biggest limitation is that it cannot be bioprinted because of
                                                               its high-temperature molten heating process, which is fatal
                                                               to cells. DIW technology (Figure 5D) has a great advantage
                 Strategy                                      in bioprinting because of its technical simplicity and the
                                                               wide range of available ink materials, such as hydrogel,


            Volume 9 Issue 6 (2023)                        327                          https://doi.org/10.36922/ijb.0969
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