Page 393 - IJB-9-6
P. 393
International Journal of Bioprinting Biomimetic biofabrication of tumors volume
Conflict of interest 6. Sajjad H, Imtiaz S, Noor T, et al., 2021, Cancer models in
preclinical research: A chronicle review of advancement in
The authors declare no conflicts of interests. effective cancer research. Anim Model Exp Med, 4(2): 87–103.
Author contributions https://doi.org/10.1002/ame2.12165
7. Li M, Song X, Jin S, et al., 2021, 3D tumor model
Conceptualization: Tarun Agarwal, Daniele Marciano, biofabrication. Bio-Design Manuf, 4(3): 526–540.
Gianluca Cidonio https://doi.org/10.1007/s42242-021-00134-7
Formal analysis: Salvatore D’Alessandro, Tarun Agarwal,
Daniele Marciano, Gianluca Cidonio 8. Celikkin N, Presutti D, Maiullari F, et al., 2021, Tackling
Investigation: Salvatore D’Alessandro, Tarun Agarwal, current biomedical challenges with frontier biofabrication
and organ-on-a-chip technologies. Front Bioeng Biotechnol, 9:
Daniele Marciano, Gianluca Cidonio 732130.
Methodology: Fabiano Bini, Salvatore D’Alessandro, Tarun
Agarwal, Daniele Marciano, Gianluca Cidonio 9. Murphy SV, Atala A, 2014, 3D bioprinting of tissues and
Funding acquisition: Giancarlo Ruocco, Gianluca Cidonio organs. Nat Biotechnol, 32(8): 773–785.
Writing – original draft: All authors https://doi.org/10.1038/nbt.2958
Writing – review & editing: Serena Duchi, Enrico Lucarelli, 10. Kakimi K, Karasaki T, Matsushita H, et al., 2017, Advances
Gianluca Cidonio in personalized cancer immunotherapy. Breast Cancer,
24(1): 16–24.
Ethics approval and consent to participate https://doi.org/10.1007/s12282-016-0688-1
Not applicable. 11. Balkwill FR, Capasso M, Hagemann T, 2012, The tumor
microenvironment at a glance. J Cell Sci, 125(23): 5591–5596.
Consent for publication https://doi.org/10.1242/jcs.116392
Not applicable. 12. Hanahan D, Weinberg RA, 2000, The hallmarks of cancer.
Cell, 100(1): 57–70.
Availability of data
13. Hanahan D, Robert AW, 2017, Biological hallmarks of
Not applicable. cancer. Holland-Frei Cancer Med, 01(April): 1–10.
https://doi.org/10.1002/9781119000822.hfcm002
References
14. Hanahan D, Coussens LM, 2012, Accessories to the crime:
1. Fitzmaurice C, Abate D, Abbasi N, et al., 2019, Global, Functions of cells recruited to the tumor microenvironment.
regional, and national cancer incidence, mortality, years of Cancer Cell, 21(3): 309–322.
life lost, years lived with disability, and disability-Adjusted https://doi.org/10.1016/j.ccr.2012.02.022
life-years for 29 cancer groups, 1990 to 2017: A systematic
analysis for the global burden of disease study. JAMA Oncol, 15. Guo S, Deng CX, 2018, Effect of stromal cells in tumor
5(12): 1749–1768. microenvironment on metastasis initiation. Int J Biol Sci,
14(14): 2083–2093.
https://doi.org/10.1001/jamaoncol.2019.2996
https://doi.org/10.7150/ijbs.25720
2. Siegel RL, Miller KD, Wagle NS, et al., 2023, Cancer statistics,
2023. CA Cancer J Clin, 73(1): 17–48. 16. Bussard KM, Mutkus L, Stumpf K, et al., 2016, Tumor-
associated stromal cells as key contributors to the tumor
https://doi.org/10.3322/caac.21763
microenvironment. Breast Cancer Res, 18(1): 1–11.
3. Bray F, Ferlay J, Soerjomataram I, et al., 2018, Global cancer
statistics 2018: GLOBOCAN estimates of incidence and https://doi.org/10.1186/s13058-016-0740-2
mortality worldwide for 36 cancers in 185 countries. CA 17. Wang W, Dai J, Huang Y, et al., 2023, Extracellular matrix
Cancer J Clin, 68(6): 394–424. mimicking dynamic interpenetrating network hydrogel for
https://doi.org/10.3322/caac.21492 skin tissue engineering. Chem Eng J, 457(November 2022):
141362.
4. Kamb A, 2005, What’s wrong with our cancer models? Nat
Rev Drug Discov, 4(2): 161–165. https://doi.org/10.1016/j.cej.2023.141362
https://doi.org/10.1038/nrd1635 18. Meacham CE, DeVilbiss AW, Morrison SJ, 2022, Metabolic
regulation of somatic stem cells in vivo. Nat Rev Mol Cell
5. Pape J, Emberton M, Cheema U, 2021, 3D cancer models: Biol, 23(6): 428–443.
The need for a complex stroma, compartmentalization and
stiffness. Front Bioeng Biotechnol, 9, 1–8. https://doi.org/10.1038/s41580-022-00462-1
Volume 9 Issue 6 (2023) 385 https://doi.org/10.36922/ijb.1022

