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International Journal of Bioprinting Bioprinted vascular tumor model

Funding 4. Li CP, Li SB, Du K, Li P, Qiu BS, Ding WP. On-chip
replication of extremely early-stage tumor behavior. Acs
This research was funded by the University Natural Science Appl Mater Inter. 2021;13(17):19768-19777.
Research Project of Anhui Province (grant number: doi: 10.1021/acsami.1c03740
2024AH051533), the Talent Research Foundation of 5. Stock K, Estrada MF, Vidic S, et al. Capturing tumor
Hefei University (grant number: 21-22RC26), the Natural complexity: comparative analysis of 2D and 3D tumor
Science Foundation of Hubei Province (grant number: models for drug discovery. Sci Rep-Uk. 2016;6:28951.
2023AFB411), and the Talent Research Foundation of doi: 10.1038/srep28951
Hefei University (grant number: 20RC40).
6. Nie J, Gao Q, Fu JZ, He Y. Grafting of 3D bioprinting
Conflict of interest to in vitro drug screening: a review. Adv Healthc Mater.
2020;9(7):e190177310.
The authors declare that they have no financial and doi: 10.1002/adhm.201901773
personal relationships with other people or organizations 7. Li JZ, Zhou YJ, Chen WL, et al. A novel 3D in vitro tumor
that can inappropriately influence the study. They also have model based on silk fibroin/chitosan scaffolds to mimic
no professional or other personal interest of any nature or the tumor microenvironment. Acs Appl Mater Inter.
kind in any product, service, and/or company that could be 2018;10(43):36641-36651.
construed as influencing the position presented in, or the doi: 10.1021/acsami.8b10679
review of, the article. 8. Lee G, Kim SJ, Park JK. Fabrication of a self-assembled and
vascularized tumor array bioprinting on a microfluidic chip.
Author contributions Lab Chip. 2023;23(18):4079-4091.
Conceptualization: Jing Liu, Haochen Liu doi: 10.1039/d3lc00275f
Formal analysis: Haizhongshi Zhang, Zhenlei Zhang 9. Nashimoto Y, Okada R, Hanada S, et al. Vascularized
Investigation: Ying Zhao, Bihan Ren, Jing Liu cancer on a chip: the effect of perfusion on growth and drug
Methodology: Dingming Li, Tianma He delivery of tumor spheroid. Biomaterials. 2020;229:119547.
Writing–original draft: Jing Liu, Ying Zhao doi: 10.1016/j.biomaterials.2019.119547
Writing–review & editing: Haochen Liu 10. Lee VK, Lanzi AM, Ngo H, Yoo SS, Vincent PA, Dai GH.
Generation of multi-scale vascular network system within
Ethics approval and consent to participate 3D hydrogel using 3D bio-printing technology. Cell Mol
Bioeng. 2014;7(3):460-472.
Not applicable. doi: 10.1007/s12195-014-0340-0

Consent for publication 11. Eckermann CW, Lehle K, Schmid SA, Wheatley DN,
Kunz-Schughart LA. Characterization and modulation of
Not applicable. fibroblast/endothelial cell co-cultures for the preformation
of three-dimensional tubular networks. Cell Biol Int.
Availability of data 2011;35(11):1097-1110.
doi: 10.1042/Cbi20100718
Data are available from the corresponding author upon
reasonable request. 12. Enzerink A, Rantanen V, Vaheri A. Fibroblast nemosis
induces angiogenic responses of endothelial cells. Exp Cell
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Volume 11 Issue 4 (2025) 389 doi: 10.36922/IJB025180180