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INNOSC Theranostics and
            Pharmacological Sciences                                           Residual versus curative antimalarial tests




            Table 1. Plants used in the management of malaria in Omu‑Aran, Nigeria
             Species name                       Family         Common name    Local name    Part used
            Tithonia diversifolia (Hemsl) A. Gray  Asteraceae  Tree marigold  June 12/Jogbo  Leaves
            Chromolaena odorata (L.) R.M king & H. Rob  Asteraceae  Siam weed  Akintola     Leaves
            Magnifera indica J.F.Macbr         Anacardiaceae  Mango           Mongoro       Leaves and stem bark
            Lawsonia inermis var. spinosa (L.) pers.  Lythraceae  Henna plants  Laali       Leaves
            Azadirachta indica A. Juss         Meliaceae      Neem            Dongoyaro     Leaves and stem bark
            Psidium guajava                    Myrtaceae      Guava           Gilofa        Leaves
            Carica papaya L.                   Caricaceae     Pawpaw          Ibepe         Leaves, root, fruits
            Gossypium barbadense L.            Malvaceae      Cotton          Owu           Leaves
            Senna siamea (Lam.) H.S irwin and Barneby  Caesalpiniaceae  Senna  Kasia        Leaves and stem bark
            Citrus aurantifolia f. aurantifolia (christm) M.Hiroe  Rutaceae  Lime  Osanwewe  Leaves and fruits
            Alstonia boonei De wild            Apocynaceae    Stool wood      Ahun          Root, stem bark and leaves
            Anacardium occidentale L.          Anacardaceae   Cashew nut tree  Kasu         Leaves
            Cymbopogon citratus stap f.        Poaceae        Lemon grass     Ewe tea       Leaves
            Enantia polycarps Engl.&Diels      Annonaceae                     Dokita Igbo   Stem bark
            Aloe vera (L.) Burnm. F            Aloeaceae      Aloe            Aloe vera     Gel
            Ocimum basilicum subsp. gratissimum  Labiatae     Sweet and hairy basil  Ejinrinwewe  Whole plant
            Axonopus compressus P. Beauv.      Poaceae        Tropical carpet grass  Idi    Leaves
            Cocos nucifera L.                  Palmae         Coconut palm    Agbon         Shaft
            Ananas comosus (L.) Merr.          Bromeliaceae   Pineapple       OpeOyinbo     Unriped fruit
            Nauclea latifolia Blanco           Rubiaceae      Nauclea African peach Ogbesi  Leaves, stem bark and root
            Nauclea diderrichii merr.          Rubiaceae      Opepe African peach  Pepe     Leaves
            Khaya grandifoliola A.Juss         Maliaceae      African Mahogany  Oganwo      Stem bark
            Morinda lucida A.Gray              Rubiaceae      Brimstone tree  Oruwo         Leaves and stem bark
            Allium sativum L.                  Liliaceae      Garlic          Ayuu          Bulb
            Kigelia africana (Lam.) Benth.     Bignoniaceae   Sausage tree    Pandoro       Leaves
            Aldama excelsa (wills) E.E school.&panero  Moraceae  Iroko        Iroko         Stem bark and leaves
            Corchorus olitorus L.              Tiliaceae      Jute plant      Ewedu         Leaves
            Ficus opposita Car.opposita now.   Labiatae       Hoshindia       Efinrin       Whole plant
            Musa paradisiaca L.                Musaceae       Plantain        OgedeAgbagba  Leaves, roots, fruit
            Musa sapientum L.                  Musaceae       Banana          Ogedeomini    Withered leaves
            Vernonia amygdalina Del.           Compositae     Bitter leaf     Ewuro         Leaves

            and the duration of treatment usually lasted for 3 – 5 days   for jaundice, hernia, and yellow fever. C.  odorata was used
            or until the symptoms disappeared. Most respondents   for skin diseases and wounds. T. diversifolia was used for
            further explained that in cases where two or more plants   managing typhoid.
            or plant parts were combined, the synergistic or additive
            effects of their constituents were exploited (Table 2).  3.2 Antimalarial activity of medicinal plants

              According to the responses, some of these medicinal   3.2.1 Curative test
            plants were  not only used for treating malaria but also
            for addressing various other diseases or purposes. For   Parasitemia was detected in the blood on day 2 post-
            example, N. latifolia was used for diabetes, pile, back pain,   infection, and subsequent monitoring revealed an increase
            and measles. L. inermis was used for hypertension, hernia,   in  parasitemia until day  9 post-infection  in both  the
            and measles, and used as cosmetics. M. lucida was used   experimental groups and negative controls. Out of the 42


            Volume 6 Issue 2 (2023)                         5                         https://doi.org/10.36922/itps.0300
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